
CAS 2030410-25-2
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Found 2 products.
PF 04449913 maleate
CAS:PF 04449913 maleate is an analog of retinoic acid, which is used in human cancer therapy. It has been shown to inhibit the proliferation of leukemia stem cells and enhance the efficacy of radiation treatment. PF 04449913 maleate has also been shown to be effective against various other types of cancer, including prostate cancer. The mechanism of action is not clear but may involve inhibition of a pump that removes retinoic acid from the cell.Formula:C25H26N6O5Purity:Min. 95%Molecular weight:490.5 g/molPF 04449913 maleate
CAS:Smo antagonist, IC50=5 nM; reduces AML cell leukemia potential and self-renewal in mice.Formula:C25H26N6O5Color and Shape:SolidMolecular weight:490.52

