The chemical substance known as (αR)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-5-fluoro-α-hydroxy-α-methyl-1H-indole-1-propanamide, with the CAS number 2031161-54-1, is a synthetic organic compound characterized by its complex structure, which includes an indole moiety, a cyano group, and a trifluoromethyl group. This compound is likely to exhibit significant biological activity due to its structural features, which may influence its interaction with biological targets. The presence of the fluorine atoms can enhance lipophilicity and metabolic stability, while the cyano group may contribute to its reactivity and potential pharmacological properties. Additionally, the α-hydroxy and α-methyl groups suggest that it may participate in hydrogen bonding and steric interactions, which are critical for its biological function. Overall, this compound's unique combination of functional groups positions it as a candidate for further research in medicinal chemistry, particularly in the development of novel therapeutic agents.

(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer[1][2].

(αR)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-5-fluoro-α-hydroxy-α-methyl-1H-indole-1-propanamide

2031161-54-1: The chemical substance known as (αR)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-5-fluoro-α-hydroxy-α-methyl-1H-indole-1-propanamide, with the CAS number 2031161-54-1, is a synthetic organic compound characterized by its complex structure, which includes an indole moiety, a cyano group, and a trifluoromethyl group. This compound is likely to exhibit significant biological activity due to its structural features, which may influence its interaction with biological targets. The presence of the fluorine atoms can enhance lipophilicity and metabolic stability, while the cyano group may contribute to its reactivity and potential pharmacological properties. Additionally, the α-hydroxy and α-methyl groups suggest that it may participate in hydrogen bonding and steric interactions, which are critical for its biological function. Overall, this compound's unique combination of functional groups positions it as a candidate for further research in medicinal chemistry, particularly in the development of novel therapeutic agents.

CAS 2031161-54-1

(αR)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-5-fluoro-α-hydroxy-α-methyl-1H-indole-1-propanamide

(R)-UT-155

Ref: TM-T13977