CAS 203120-46-1

Laninamivir octanoate

Description:

Laninamivir octanoate is an antiviral compound primarily used in the treatment of influenza. It is a prodrug of laninamivir, which means it is converted into its active form within the body. This compound exhibits characteristics typical of neuraminidase inhibitors, which work by blocking the viral enzyme responsible for the release of new viral particles from infected cells, thereby limiting the spread of the virus. Laninamivir octanoate is known for its long half-life, allowing for less frequent dosing compared to other antiviral medications. It is administered via inhalation, which facilitates direct delivery to the respiratory tract, where influenza viruses primarily replicate. The compound is generally well-tolerated, with a safety profile that includes mild to moderate side effects. Its efficacy against various strains of influenza, including those resistant to other antiviral agents, makes it a valuable option in antiviral therapy. As with any medication, it is important to consider potential interactions and contraindications when prescribing laninamivir octanoate.

Formula: C₂₁H₃₆N₄O₈

InChI: InChI=1S/C21H36N4O8/c1-4-5-6-7-8-9-16(28)32-11-14(27)18(31-3)19-17(24-12(2)26)13(25-21(22)23)10-15(33-19)20(29)30/h10,13-14,17-19,27H,4-9,11H2,1-3H3,(H,24,26)(H,29,30)(H4,22,23,25)/t13-,14+,17+,18+,19+/m0/s1

InChI key: InChIKey=UKTIJASCFRNWCB-RMIBSVFLSA-N

SMILES: N(C(C)=O)[C@H]1[C@]([C@@H]([C@@H](COC(CCCCCCC)=O)O)OC)(OC(C(O)=O)=C[C@@H]1NC(=N)N)[H]

Synonyms:

• Laninamivir octanoate
• D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-O-methyl-, 9-octanoate
• (2R,3R,4S)-3-Acetamido-4-guanidino-2-[(1R,2R)-2-hydroxy-1-methoxy-3-(octanoyloxy)propyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
• CS 8958
• (4S,5R,6R)-5-Acetamido-4-guanidino-6-[(1R,2R)-2-hydroxy-1-methoxy-3-(octanoyloxy)propyl]-5,6-dihydro-4H-pyran-2-carboxylic acid
• (2R,3R,4S)-3-Acetamido-4-guanidino-2-[(1R,2R)-2-hydroxy-1-methoxy-3-(octanoyloxy)propyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
• D-Glycero-D-galacto-non-2-enonic acid 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-O-methyl-9-octanoate
• Laninamivir Octanoate Hydrate
• laninamivir octanoate USP/EP/BP

Laninamivir octanoate

CAS: 203120-46-1

Laninamivir octanoate

Purity: ≥98%

Molecular weight: 472.53g/mol

Ref: 54-BUP12263

Laninamivir Octanoate

CAS: 203120-46-1

Formula: C₂₁H₃₆N₄O₈

Molecular weight: 472.54

Ref: 4Z-L-222002

Laninamivir octanoate

CAS: 203120-46-1

Laninamivir octanoate (CS-8958) is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity.

Formula: C₂₁H₃₆N₄O₈

Purity: 99.61% - 99.90%

Color and Shape: Solid

Molecular weight: 472.53

Ref: TM-T9124

Laninamivir Octanoate-d3

Controlled Product

CAS: 203120-46-1

Formula: C₂₁D₃H₃₃N₄O₈

Color and Shape: Neat

Molecular weight: 475.551

Ref: TR-L174012

Laninamivir Octanoate

Controlled Product

CAS: 203120-46-1

Applications: Laninamivir (L174000) prodrug; a novel long-acting neuraminidase inhibitor.
References Neumann, G., et al.: Nature, 459, 931 (2009), Yamashita, M., et al.: Antimicrob. Agents Chemother., 53, 186 (2009),

Formula: C₂₁H₃₆N₄O₈

Color and Shape: Neat

Molecular weight: 472.53

Ref: TR-L174010