CAS 203395-82-8

7-[4-[4-(3-Chlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone

Description:

The chemical substance known as 7-[4-[4-(3-Chlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone, with the CAS number 203395-82-8, is a synthetic organic compound characterized by its complex molecular structure. It features a quinolinone core, which is a bicyclic compound known for its diverse biological activities. The presence of a piperazine moiety contributes to its potential pharmacological properties, often associated with neuroactive compounds. The chlorophenyl group enhances its lipophilicity, potentially influencing its ability to cross biological membranes. This compound may exhibit various interactions with biological targets, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific characteristics, such as solubility, stability, and reactivity, would depend on the functional groups present and the overall molecular conformation. As with many compounds in this class, understanding its structure-activity relationship is crucial for predicting its behavior in biological systems and its potential applications in drug development.

Formula: C₂₃H₂₈ClN₃O₂

InChI: InChI=1S/C23H28ClN3O2/c24-19-4-3-5-20(16-19)27-13-11-26(12-14-27)10-1-2-15-29-21-8-6-18-7-9-23(28)25-22(18)17-21/h3-6,8,16-17H,1-2,7,9-15H2,(H,25,28)

InChI key: InChIKey=SHHUSQIOAKPGMO-UHFFFAOYSA-N

SMILES: O(CCCCN1CCN(CC1)C2=CC(Cl)=CC=C2)C=3C=C4C(=CC3)CCC(=O)N4

Synonyms:

• 2(1H)-Quinolinone, 7-[4-[4-(3-chlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-
• 7-[4-[4-(3-Chlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone

2-Dechloro Aripiprazole (7-(4-(4-(3-chlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one)

CAS: 203395-82-8

Lactams, nesoi

Formula: C₂₃H₂₈ClN₃O₂

Color and Shape: White Off-White Solid

Molecular weight: 413.187

Ref: 45-1A02450

2-Deschloro Aripiprazole

CAS: 203395-82-8

Formula: C₂₃H₂₈ClN₃O₂

Color and Shape: Solid

Molecular weight: 413.9403

Ref: IN-DA00C2CM

Aripiprazole EP Impurity D

CAS: 203395-82-8

Formula: C₂₃H₂₈ClN₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 413.95

Ref: 4Z-A-1412

7-[4-[4-(3-Chlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydroquinolin-2(1H)-one

Controlled Product

CAS: 203395-82-8

Formula: C₂₃H₂₈ClN₃O₂

Color and Shape: Neat

Molecular weight: 413.94

Ref: 86-MM0961.07

2-Deschloro Aripiprazole

CAS: 203395-82-8

Impurity Aripiprazole EP Impurity D
Applications 2-Deschloro Aripiprazole (Aripiprazole EP Impurity D) is an impurity of the antipsychotic agent Aripiprazole (A771000). Aripiprazole impurity B.
References Akaike, A., et al.: Brain Res., 418, 262 (1987); Kikuchi, K., et al.: Life Sci., 42, 343 (1988); Caprathe, B., et al.: J. Med. Chem., 34, 2736 (1991); Yamada, S., et al.: J. Pharm. Pharmacol., 49, 206 (1997);

Formula: C₂₃H₂₈ClN₃O₂

Color and Shape: White

Molecular weight: 413.94

Ref: TR-D282020

Aripiprazole EP Impurity D

CAS: 203395-82-8

Formula: C₂₃H₂₈ClN₃O₂

Molecular weight: 413.94

Ref: ST-EA-CP-A22004

2-Deschloro aripiprazole

CAS: 203395-82-8

2-Deschloro aripiprazole is a drug that belongs to the class of antipsychotics. It is an atypical antipsychotic with a high affinity for human albumin and α1-acid glycoprotein, which are plasma proteins. 2-Deschloro aripiprazole has been shown to interact with human albumin and α1-acid glycoprotein in vitro, and it has been suggested that this interaction may be responsible for its pharmacological effects. 2-Deschloro aripiprazole has also been shown to bind to the dopamine D2 receptor, which is thought to be responsible for its therapeutic effects as an antipsychotic. The molecular interactions between 2-deschloro aripiprazole and human albumin have been studied using isothermal titration calorimetry (ITC) and molecular docking studies. These studies have helped us understand how 2-deschloro aripiprazole binds to human album

Formula: C₂₃H₂₈ClN₃O₂

Purity: Min. 95%

Molecular weight: 413.94 g/mol

Ref: 3D-ID171125