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CAS 203636-26-4

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Fmoc-Aib-OPfp

Description:
Fmoc-Aib-OPfp is a chemical compound commonly used in peptide synthesis and research. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. "Aib" refers to α-aminoisobutyric acid, a non-proteinogenic amino acid that introduces structural rigidity and influences the conformation of peptides. The "OPfp" part indicates the presence of a pentafluorophenyl (Pfp) ester, which is a reactive moiety that facilitates the coupling of amino acids during synthesis. This compound is typically utilized in solid-phase peptide synthesis (SPPS) due to its stability and ease of handling. Its characteristics include good solubility in organic solvents, stability under standard laboratory conditions, and the ability to undergo selective reactions that are crucial for constructing complex peptide sequences. Overall, Fmoc-Aib-OPfp is valued for its role in producing peptides with specific structural and functional properties in biochemical research and pharmaceutical applications.
Formula:C25H18F5NO4
Synonyms:
  • N-Alpha- Fmoc-Alpha-Aminoisobutyric Acid Pentafluorophenyl Ester
  • Fmoc-Alpha-Aminoisobutyric Acid Pentafluorophenyl Ester
  • Fmoc-Alpha-Methylalanine Pentafluorophenyl Ester
  • N-Α-Fmoc-Α-Aminoisobutyricacidpentafluorophenylester
  • Alanine,N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-2-Methyl-, Pentafluorophenyl Ester
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Purity (%)
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100
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0
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50
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90
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95
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100
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