CAS 203866-15-3

1-(1,1-Dimethylethyl) (2S)-4,4-difluoro-1,2-pyrrolidinedicarboxylate

Description:

1-(1,1-Dimethylethyl) (2S)-4,4-difluoro-1,2-pyrrolidinedicarboxylate, with CAS number 203866-15-3, is a chemical compound characterized by its pyrrolidine structure, which includes two carboxylate functional groups and two fluorine atoms attached to the carbon backbone. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and specific formulation. It is known for its potential applications in medicinal chemistry and as an intermediate in organic synthesis. The presence of the bulky tert-butyl group (1,1-dimethylethyl) contributes to its steric hindrance, which can influence its reactivity and interactions with biological targets. The difluoromethyl substituents can enhance lipophilicity and alter the electronic properties of the molecule, making it of interest in drug design. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken due to potential toxicity or reactivity.

Formula: C₁₀H₁₅F₂NO₄

InChI: InChI=1S/C10H15F2NO4/c1-9(2,3)17-8(16)13-5-10(11,12)4-6(13)7(14)15/h6H,4-5H2,1-3H3,(H,14,15)/t6-/m0/s1

InChI key: InChIKey=WTMZYKCXBXPVPT-LURJTMIESA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@H](C(O)=O)CC(F)(F)C1

Synonyms:

• (2S)-1-(tert-Butoxycarbonyl)-4,4-difluoro-2-pyrrolidinecarboxylic acid
• (2S)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
• (2S)-1-[(tert-butoxy)carbonyl]-4,4-difluoropyrrolidine-2-carboxylic acid
• (2S)-4,4-Difluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• (S)-1-(tert-butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
• 1,2-Pyrrolidinedicarboxylic acid, 4,4-difluoro-, 1-(1,1-dimethylethyl) ester, (2S)-
• 1,2-Pyrrolidinedicarboxylic acid, 4,4-difluoro-, 1-(1,1-dimethylethyl) ester, (S)-
• 1-(1,1-Dimethylethyl) (2S)-4,4-difluoro-1,2-pyrrolidinedicarboxylate
• 1-(tert-Butoxycarbonyl)-4,4-difluoro-L-proline
• 4,4-Difluoro-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
• N-Boc-4,4-difluoro-<span class="text-smallcaps">L</span>-proline

N-Boc-4,4-difluoro-L-proline, 97+%

CAS: 203866-15-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₅F₂NO₄

Purity: 97+%

Color and Shape: Crystals or powder or crystalline powder, White to cream

Molecular weight: 251.24

Ref: 02-H27052

1,2-Pyrrolidinedicarboxylic acid, 4,4-difluoro-, 1-(1,1-dimethylethyl) ester, (2S)-

CAS: 203866-15-3

Formula: C₁₀H₁₅F₂NO₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 251.2272

Ref: IN-DA00295P

N-BOC-4,4-Difluoro-L-proline

CAS: 203866-15-3

N-BOC-4,4-Difluoro-L-proline

Formula: C₁₀H₁₅F₂NO₄

Purity: 98%

Color and Shape: pale brown solid

Molecular weight: 251.23g/mol

Ref: 54-PC409001

(S)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid

CAS: 203866-15-3

Formula: C₁₀H₁₅F₂NO₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 251.23

Ref: 10-F236959