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CAS 203866-20-0

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(4R)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-proline

Description:
(4R)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-proline is a synthetic amino acid derivative characterized by its unique structural features, which include a proline backbone modified with a fluoro group and a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is notable for its chirality, specifically the (4R) configuration, which plays a crucial role in its biological activity and interactions. The presence of the fluoro substituent can enhance the compound's stability and influence its pharmacological properties, making it of interest in medicinal chemistry and peptide synthesis. The Fmoc group serves as a protective moiety that facilitates the synthesis of peptides by allowing selective deprotection under mild conditions. This compound is often utilized in the development of peptide-based therapeutics and in research related to protein engineering. Its unique characteristics make it a valuable tool in the study of structure-activity relationships in drug design and development.
Formula:C20H18FNO4
InChI:InChI=1/C20H18FNO4/c21-12-9-18(19(23)24)22(10-12)20(25)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17-18H,9-11H2,(H,23,24)/t12-,18+/m1/s1
Synonyms:
  • Fmoc-trans-4-fluoro-Pro-OH
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