CymitQuimica logo

CAS 203869-80-1

:

1-(tert-butoxycarbonyl)-2-methylproline

Description:
1-(tert-Butoxycarbonyl)-2-methylproline, with the CAS number 203869-80-1, is a derivative of proline, an amino acid commonly found in proteins. This compound features a tert-butoxycarbonyl (Boc) protecting group, which is often used in organic synthesis to protect amine functionalities during chemical reactions. The presence of the methyl group at the 2-position of the proline ring introduces steric hindrance, influencing the compound's reactivity and conformational properties. Typically, this compound is a white to off-white solid, and it is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but less soluble in water. Its structure allows for potential applications in peptide synthesis and drug development, particularly in the design of proline-based compounds. The Boc group can be removed under acidic conditions, facilitating further functionalization of the proline moiety. Overall, 1-(tert-butoxycarbonyl)-2-methylproline is a valuable intermediate in synthetic organic chemistry, particularly in the field of medicinal chemistry.
Formula:C11H19NO4
InChI:InChI=1/C11H19NO4/c1-10(2,3)16-9(15)12-7-5-6-11(12,4)8(13)14/h5-7H2,1-4H3,(H,13,14)
SMILES:CC(C)(C)OC(=O)N1CCCC1(C)C(=O)O
Synonyms:
  • 1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester
  • 1-Boc-2-Methyl-DL-Proline
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.