CAS 203923-89-1

Karenitecin

Description:

Karenitecin is a chemical compound classified as a natural product, specifically a type of alkaloid. It is derived from certain species of fungi and has garnered interest due to its potential pharmacological properties. The compound is known for its complex molecular structure, which contributes to its biological activity. Karenitecin exhibits antitumor properties, making it a subject of research in cancer therapeutics. Its mechanism of action typically involves interference with cellular processes, potentially leading to apoptosis in cancer cells. Additionally, the compound may possess antimicrobial and anti-inflammatory effects, further expanding its potential applications in medicine. As with many natural products, the extraction and purification of karenitecin can be challenging, and its stability under various conditions is an important consideration in research and development. Overall, karenitecin represents a promising area of study in the field of medicinal chemistry, with ongoing investigations into its efficacy and safety profiles.

Formula: C₂₅H₂₈N₂O₄Si

InChI: InChI=1/C25H28N2O4Si/c1-5-25(30)19-12-21-22-17(13-27(21)23(28)18(19)14-31-24(25)29)15(10-11-32(2,3)4)16-8-6-7-9-20(16)26-22/h6-9,12,30H,5,10-11,13-14H2,1-4H3/t25-/m0/s1

SMILES: CC[C@@]1(c2cc3c4c(Cn3c(=O)c2COC1=O)c(CC[Si](C)(C)C)c1ccccc1n4)O

Synonyms:

• (4S)-4-Ethyl-4-hydroxy-11-(2-trimethylsilyl)ethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

(4S)-4-Ethyl-4-hydroxy-11-[2-(trimethylsilyl)ethyl]-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

CAS: 203923-89-1

Formula: C₂₅H₂₈N₂O₄Si

Purity: 98.27%

Color and Shape: Solid

Molecular weight: 448.5863

Ref: IN-DA00297R

(S)-4-Ethyl-4-hydroxy-11-(2-(trimethylsilyl)ethyl)-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

CAS: 203923-89-1

(S)-4-Ethyl-4-hydroxy-11-(2-(trimethylsilyl)ethyl)-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

Purity: 95%

Molecular weight: 448.6g/mol

Ref: 54-OR1070284

Karenitecin

Controlled Product

CAS: 203923-89-1

Formula: C₂₅H₂₈N₂O₄Si

Color and Shape: Neat

Molecular weight: 448.586

Ref: TR-K452260

Karenitecin

CAS: 203923-89-1

Karenitecin is a diagnostic agent with minimal toxicity. It is used to detect granulosa cells in human serum and is also an immunohistochemical marker for the diagnosis of gliomas. Karenitecin binds to α1-acid glycoprotein, which is found at high levels in plasma and cerebrospinal fluid, and has been shown to have potent antitumor activity. The drug can be administered intravenously or intra-arterially, with a low risk of toxicity. Karenitecin has been shown to have antineoplastic properties by inhibiting mitochondrial membrane potential, which may be due to its ability to bind to the a-ring of ATP synthase.

Formula: C₂₅H₂₈N₂O₄Si

Purity: Min. 95%

Molecular weight: 448.6 g/mol

Ref: 3D-DIA92389

Karenitecin

CAS: 203923-89-1

Karenitecin (Cositecan) is an inhibitor of topoisomerase I. It has potent anti-cancer activity.

Formula: C₂₅H₂₈N₂O₄Si

Purity: 98%

Color and Shape: Solid

Molecular weight: 448.59

Ref: TM-T14703