CAS 20410-95-1

(5α,6α)-4,5-Epoxy-17-(2-propen-1-yl)morphinan-3,6,14-triol

Description:

The chemical substance known as (5α,6α)-4,5-Epoxy-17-(2-propen-1-yl)morphinan-3,6,14-triol, with the CAS number 20410-95-1, is a morphinan derivative characterized by its complex polycyclic structure. This compound features an epoxy group at the 4,5 positions, which contributes to its reactivity and potential biological activity. The presence of a propenyl group at the 17 position suggests that it may exhibit unique pharmacological properties, possibly influencing its interaction with biological targets such as opioid receptors. The triol functional groups at the 3, 6, and 14 positions indicate that it has multiple hydroxyl groups, which can enhance solubility and reactivity. This compound is of interest in medicinal chemistry, particularly in the development of analgesics or other therapeutic agents. Its stereochemistry, denoted by the 5α and 6α configurations, is crucial for its biological activity, as stereoisomers can exhibit significantly different effects in biological systems. Overall, this substance represents a fascinating area of study within the field of organic and medicinal chemistry.

Formula: C₁₉H₂₃NO₄

InChI: InChI=1S/C19H23NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,13-14,17,21-23H,1,5-10H2/t13-,14+,17-,18-,19+/m0/s1

InChI key: InChIKey=HMWHERQFMBEHNG-AQQQZIQISA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3([C@@H](O)CC1)[H])=C(O)C=CC5C[C@]2(N(CC=C)CC4)[H]

Synonyms:

• (5alpha,6alpha)-4,5-Epoxy-17-(2-propenyl)morphinan-3,6,14-triol
• (5α,6α)-4,5-Epoxy-17-(2-propen-1-yl)morphinan-3,6,14-triol
• 6-Hydroxynaloxone
• 6α-Naloxol
• En 2265
• Morphinan-3,6,14-triol, 4,5-epoxy-17-(2-propen-1-yl)-, (5α,6α)-
• Morphinan-3,6,14-triol, 4,5-epoxy-17-(2-propenyl)-, (5α,6α)-
• Morphinan-3,6α,14-triol, 17-allyl-4,5α-epoxy-
• N-Allyl-14-hydroxy-7,8-dihydronormorphine
• N-Allyl-7,8-dihydro-14-hydroxynormorphine
• α-Naloxol

6-α Naloxol

CAS: 20410-95-1

6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist and is a human metabolite of naloxone.

Formula: C₁₉H₂₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 329.39

Ref: TM-T10180

6α-Naloxol-d5 Hydrochloride

Controlled Product

CAS: 20410-95-1

Applications A labelled metabolite of Naloxone (N285000). Naltrexone analog and Naloxone analog neutral µ opioid antagonists and use thereof in treating drug abuse and pain.
References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975), Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996), Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000),

Formula: C₁₉D₅H₁₈NO₄·HCl

Color and Shape: Neat

Molecular weight: 370.882

Ref: TR-N284502

6a-Naloxol

Controlled Product

CAS: 20410-95-1

Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.
References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)

Formula: C₁₉H₂₃NO₄

Color and Shape: Neat

Molecular weight: 329.39

Ref: TR-N284495

6-α-Naloxol (1.0mg/ml in Acetonitrile)

Controlled Product

CAS: 20410-95-1

Formula: C₁₉H₂₃NO₄

Color and Shape: Single Solution

Molecular weight: 329.39

Ref: TR-KIT6370

6α-Naloxol

Controlled Product

CAS: 20410-95-1

Please enquire for more information about 6Alpha-Naloxol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₉H₂₃NO₄

Purity: Min. 95%

Molecular weight: 329.4 g/mol

Ref: 3D-VAA41095