CAS 204204-73-9

(2Z)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]acetic acid

Description:

The chemical substance known as (2Z)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]acetic acid, with the CAS number 204204-73-9, is characterized by its complex molecular structure, which includes a cyclopropyl group, a fluorophenyl moiety, and a piperidine ring. This compound features a mercapto group, indicating the presence of a thiol functional group, which can contribute to its reactivity and potential biological activity. The acetic acid component suggests that it may exhibit acidic properties, influencing its solubility and interaction with biological systems. The presence of multiple functional groups implies that this compound could engage in various chemical reactions, making it of interest in medicinal chemistry and drug development. Its specific stereochemistry, indicated by the (2Z) configuration, may also play a crucial role in its biological activity and pharmacokinetics. Overall, this compound's unique structural features position it as a candidate for further investigation in therapeutic applications.

Formula: C₁₈H₂₀FNO₃S

InChI: InChI=1/C18H20FNO3S/c19-14-4-2-1-3-13(14)17(18(23)11-5-6-11)20-8-7-15(24)12(10-20)9-16(21)22/h1-4,9,11,15,17,24H,5-8,10H2,(H,21,22)/b12-9-

InChI key: InChIKey=ZWUQVNSJSJHFPS-XFXZXTDPNA-N

SMILES: C(C(=O)C1CC1)(N2C\C(=C\C(O)=O)\C(S)CC2)C3=C(F)C=CC=C3

Synonyms:

• Acetic acid, 2-[1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-, (2Z)-
• Acetic acid, [1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-, (Z)-
• R 138727
• Acetic acid, [1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-, (2Z)-
• (2Z)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]acetic acid
• cis R-138727, (Prasugrel Metabolite) DISCONTINUED
• (Z)-2-(1-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4-mercaptopiperidin-3-ylidene)acetic Acid
• R-138727 , CID 10405534
• R-138727 (Prasugrel Metabolite)
• PRASUGREL METABOLITE R-138727 98.0%
• 2-[1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulfanylpiperidin-3-ylidene]acetic acid
• PRASUGREL METABOLITE R-138727
• Prasugrel Metabolite R
• Discontinued
• Prasugrel-d4 Metabolite R-138727
• (2Z)-2-[1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulfanylpiperidin-3-ylidene]acetic acid
• Prasugrel Metabolite R-138727 HCl (Mixture of Diastereomers)
• cis R-138727, (Prasugrel Metabolite)
• (Mixture of Diastereomers)
• Prasugrel Active Metabolite R138727

(Z)-2-(1-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4-mercaptopiperidin-3-ylidene)acetic acid

CAS: 204204-73-9

Formula: C₁₈H₂₀FNO₃S

Molecular weight: 349.4197

Ref: IN-DA0029CE

R-138727

CAS: 204204-73-9

R-138727 is a novel P2Y12 receptor inhibitor.

Formula: C₁₈H₂₀FNO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 349.42

Ref: TM-T19667

R-138727

CAS: 204204-73-9

R-138727 is a peptide that has been shown to activate the human ATP-sensitive potassium channel (KATP) in a dose dependent manner. This peptide has been shown to inhibit the activity of the KATP channel by binding to it and preventing it from opening. R-138727 has also been shown to inhibit protein interactions with its ligand, which may be due to its ability to compete with other proteins for access to the ligand. The IC50 value for R-138727 was found to be 0.5 μM in a competitive inhibition assay.
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Formula: C₁₈H₂₀FNO₃S

Purity: Min. 95%

Molecular weight: 349.4 g/mol

Ref: 3D-EIA20473