CAS 20426-12-4

4-Hydroxychalcone

Description:

4-Hydroxychalcone is an organic compound belonging to the chalcone family, characterized by its structure that includes a phenolic hydroxyl group and a ketone group. It typically appears as a yellow to orange crystalline solid and is known for its role as a flavonoid precursor in various biological systems. The compound exhibits notable antioxidant properties, which contribute to its potential health benefits, including anti-inflammatory and antimicrobial activities. 4-Hydroxychalcone is soluble in organic solvents such as ethanol and methanol but has limited solubility in water. Its chemical formula is C15H12O3, and it has a molecular weight that reflects its composition of carbon, hydrogen, and oxygen atoms. This compound is of interest in both synthetic organic chemistry and pharmacology, as it can serve as a building block for the synthesis of more complex flavonoids and may have applications in the development of therapeutic agents. Additionally, its structural features allow for various chemical modifications, enhancing its utility in research and industry.

Formula: C₁₅H₁₂O₂

InChI: InChI=1/C15H12O2/c16-14-9-6-12(7-10-14)8-11-15(17)13-4-2-1-3-5-13/h1-11,16H/b11-8+

InChI key: InChIKey=PWWCDTYUYPOAIU-UHFFFAOYSA-N

SMILES: C(C=CC1=CC=C(O)C=C1)(=O)C2=CC=CC=C2

Synonyms:

• (2E)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one
• (4-Hydroxybenzal)acetophenone
• (4-Hydroxybenzylidene)acetophenone
• 1-Phenyl-3-(4-hydroxyphenyl)-2-propen-1-one
• 2-Propen-1-one, 3-(4-hydroxyphenyl)-1-phenyl-
• 3-(4-Hydroxyphenyl)-1-Phenylprop-2-En-1-One
• 3-(4-Hydroxyphenyl)-1-phenyl-2-propen-1-one
• 4-Hydroxybenzylideneacetophenone
• 4-Hydroxystyryl phenyl ketone
• Chalcone, 4-hydroxy-
• NSC 60593
• p-Hydroxychalcone
• 4-Hydroxychalcone
• 1-Phenyl-3-(4-hydroxyphenyl)-2-propene-1-one
• 2-(4-HYDROXYBENZAL)ACETOPHENONE
• 2-(4-HYDROXYBENZYLIDENE)ACETOPHENONE
• BENZYLIDENE-4-HYDROXYACETOPHENONE
• (E)-3-(4-HYDROXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE

(E)-4-Hydroxychalcone

CAS: 20426-12-4, 38239-55-3

Formula: C₁₅H₁₂O₂

Purity: >97.0%(T)(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 224.26

Ref: 3B-H0955

4-Hydroxychalcone

CAS: 20426-12-4

4-Hydroxychalcone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₅H₁₂O₂

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 224.27

Ref: 11-1272

2-Propen-1-one, 3-(4-hydroxyphenyl)-1-phenyl-

CAS: 20426-12-4

Formula: C₁₅H₁₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 224.2546

Ref: IN-DA0029DH

4-Hydroxychalcone

CAS: 20426-12-4

4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.

Formula: C₁₅H₁₂O₂

Purity: 99.75%

Color and Shape: Yellow Powder

Molecular weight: 224.25

Ref: TM-T3005

4-Hydroxychalcone

CAS: 20426-12-4

4-Hydroxychalcone

Purity: 97%

Color and Shape: Solid

Molecular weight: 224.25g/mol

Ref: 54-OR1234

4-Hydroxychalcone

CAS: 20426-12-4

4-Hydroxychalcone

Purity: ≥98%

Molecular weight: 224.25g/mol

Ref: 54-BUP16538

4-Hydroxychalcone

CAS: 20426-12-4

Formula: C₁₅H₁₂O₂

Purity: 97.0%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 224.259

Ref: 10-F003114

4-Hydroxybenzylidene acetophenone

CAS: 20426-12-4

4-Hydroxybenzylidene acetophenone is a natural compound that has been shown to exhibit cytotoxic activity against human cancer cells. It inhibits the production of TNF-α and reactive oxygen species, and increases mitochondrial membrane potential in MCF-7 cells. The mechanism of action of 4-Hydroxybenzylidene acetophenone involves binding to the heme group of cytochrome P450 and altering its reactivity. This compound has been proposed as a possible analytical method for determining the amount of reactive oxygen species present in biological samples.

Formula: C₁₅H₁₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 224.25 g/mol

Ref: 3D-FH70053

4-Hydroxychalcone, 97%

CAS: 20426-12-4

4-Hydroxychalcone is used as anti-angiogenesis, antineoplastic. It is also used as organic intermediates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa

Formula: C₁₅H₁₂O₂

Purity: 97%

Color and Shape: Yellow, Crystals or powder or crystalline powder

Molecular weight: 224.26

Ref: 02-A15307