CAS 2043-38-1

butizide

Description:

Butizide, with the CAS number 2043-38-1, is a chemical compound that belongs to the class of sulfonamide derivatives. It is primarily recognized for its application as a diuretic and antihypertensive agent. The compound exhibits properties that facilitate the inhibition of sodium reabsorption in the kidneys, leading to increased urine production and a reduction in blood pressure. Butizide is typically characterized by its moderate solubility in water and organic solvents, which influences its bioavailability and pharmacokinetics. The chemical structure of butizide includes a sulfonamide group, which is essential for its biological activity. Additionally, it may have various side effects, including electrolyte imbalances, which necessitate careful monitoring during therapeutic use. As with many pharmaceuticals, the safety and efficacy of butizide are determined through clinical studies, and it is essential to adhere to prescribed dosages to minimize potential adverse effects. Overall, butizide serves as an important compound in the management of certain cardiovascular conditions.

Formula: C₁₁H₁₆ClN₃O₄S₂

InChI: InChI=1/C11H16ClN3O4S2/c1-6(2)3-11-14-8-4-7(12)9(20(13,16)17)5-10(8)21(18,19)15-11/h4-6,11,14-15H,3H2,1-2H3,(H2,13,16,17)

InChI key: InChIKey=HGBFRHCDYZJRAO-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(NC(CC(C)C)N1)=CC(Cl)=C(S(N)(=O)=O)C2

Synonyms:

• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(2-methylpropyl)-, 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-isobutyl-, 1,1-dioxide
• 3-Isobutyl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 3500S
• 6-Chloro-3,4-Dihydro-3-Isobutyl-1,2,4-Benzothiadiazine-7-Sulphonamide 1,1-Dioxide
• 6-chloro-3-(2-methylpropyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Buthiazide
• Butizid
• Eunephran
• Isobutylhydrochlorothiazide
• Modenol
• S 3500
• Saltucin
• Su 6187
• Thiabutazide
• Butizide
• Butizidum
• 6-Chloro-3,4-dihydro-3-(2-Methylpropyl)-2H-1,2,4-benzothiadiazine-7-sulfonaMide 1,1-Dioxide
• 6-chloro-3-(2-methylpropyl)-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide

Buthiazide

Controlled Product

CAS: 2043-38-1

Applications Diuretic and antihypertensive.
References Fuster, D., et al.: Endocrinol., 139, 3849 (1998), Selvaag, E., et al.: Photodermatol., Photoimmunol., Photomed., 18, 90 (2002), Beyer, J., et al.: Ther. Drug Monitor., 27, 509 (2005),

Formula: C₁₁H₁₆ClN₃O₄S₂

Color and Shape: Neat

Molecular weight: 353.85

Ref: TR-B690035

Buthiazide

CAS: 2043-38-1

Buthiazide is a diuretic drug that is used to treat high blood pressure. It is also used to treat bowel disease and cardiac problems such as congestive heart failure. Buthiazide can be used in tissue culture to control the effects of cardiac cells on cardiac function. The drug has been shown to reduce the expression of proprotein convertase subtilisin/kexin type 9 (PCSK9) in human serum. Buthiazide is also effective in reducing inflammation in the digestive system, by inhibiting the production of fatty acid and protein genes that are involved in inflammatory bowel disease.

Formula: C₁₁H₁₆ClN₃O₄S₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 353.85 g/mol

Ref: 3D-FB19384

Buthiazide

CAS: 2043-38-1

Buthiazide, also known as Butizide, is a 3-isobutyl analog of hydrochlorothiazide.

Formula: C₁₁H₁₆ClN₃O₄S₂

Color and Shape: Solid

Molecular weight: 353.85

Ref: TM-T30624