CAS 204316-36-9

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-L-alanine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-L-alanine, commonly referred to as Fmoc-L-Ala(PhO)-OH, is a protected amino acid used primarily in peptide synthesis. This compound features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The presence of the phenylmethoxycarbonyl (PhO) group further enhances its stability and solubility in organic solvents. The structure includes a chiral L-alanine backbone, contributing to its utility in synthesizing peptides with specific stereochemistry. This compound is typically white to off-white in appearance and is soluble in common organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its stability under standard laboratory conditions makes it a valuable intermediate in the synthesis of complex peptides and proteins. Additionally, the use of Fmoc chemistry allows for easy removal of the protective group under mild basic conditions, facilitating the sequential addition of amino acids in solid-phase peptide synthesis.

Formula: C₂₆H₂₄N₂O₆

InChI: InChI=1S/C26H24N2O6/c29-24(30)23(14-27-25(31)33-15-17-8-2-1-3-9-17)28-26(32)34-16-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,27,31)(H,28,32)(H,29,30)/t23-/m0/s1

InChI key: InChIKey=CDAHZCMBWKGJEC-QHCPKHFHSA-N

SMILES: C(OC(N[C@@H](CNC(OCC1=CC=CC=C1)=O)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• <span class="text-smallcaps">L</span>-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-
• Fmoc-Dap(Z)-Oh
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-<span class="text-smallcaps">L</span>-alanine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-L-alanine
• L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-

L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-

CAS: 204316-36-9

Formula: C₂₆H₂₄N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 460.4786

Ref: IN-DA0029EF

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(((benzyloxy)carbonyl)amino)propanoic acid

CAS: 204316-36-9

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(((benzyloxy)carbonyl)amino)propanoic acid

Purity: 98%

Molecular weight: 460.48g/mol

Ref: 54-OR95536

Fmoc-Dap(Z)-OH

CAS: 204316-36-9

Molecular weight: 460.48

Ref: 7W-GM8216

Fmoc-Dap(Z)-OH

CAS: 204316-36-9

Fmoc-Dap(Z)-OH is a versatile building block that has been used as a reagent, speciality chemical and useful intermediate. It has also been used in the synthesis of pharmaceuticals, such as anti-inflammatory drugs and antibiotics. Fmoc-Dap(Z)-OH is an important building block for the synthesis of complex compounds with high quality and useful scaffolds.

Formula: C₂₆H₂₄N₂O₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 460.48 g/mol

Ref: 3D-FF72255

(2S)-3-N-Cbz-Amino-2-N-Fmoc-amino-propionic acid

CAS: 204316-36-9

Formula: C₂₆H₂₄N₂O₆

Purity: 98%

Color and Shape: No data available.

Molecular weight: 460.486

Ref: 10-F048984