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CAS 204322-23-6

:

Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid

Description:
Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid is a chemical compound that belongs to the class of amino acids and derivatives, specifically designed for use in peptide synthesis and drug development. The "Fmoc" (9-fluorenylmethoxycarbonyl) group is a common protecting group used in solid-phase peptide synthesis, providing stability and facilitating the selective deprotection of amino acids. The compound features a tetrahydronorharman structure, which is a bicyclic compound known for its potential biological activity, including neuroprotective and antidepressant properties. The carboxylic acid functional group contributes to its acidity and reactivity, allowing for further chemical modifications. This compound is typically utilized in research settings, particularly in the synthesis of peptides that may exhibit therapeutic effects. Its unique structural features and functional groups make it a valuable building block in medicinal chemistry and biochemistry. As with many chemical substances, proper handling and safety precautions are essential due to potential hazards associated with its use.
Formula:C27H22N2O4
InChI:InChI=1/C27H22N2O4/c30-26(31)25-13-21-20-11-5-6-12-23(20)28-24(21)14-29(25)27(32)33-15-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-12,22,25,28H,13-15H2,(H,30,31)/t25-/m0/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=O)N1Cc2c(C[C@H]1C(=O)O)c1ccccc1[nH]2
Synonyms:
  • Fmoc-L-Tpi-OH
  • (3S)-2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
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