CAS 20443-98-5

2,6-Dichlorobenzyl bromide

Description:

2,6-Dichlorobenzyl bromide is an organic compound characterized by its aromatic structure, featuring a benzene ring substituted with two chlorine atoms at the 2 and 6 positions and a bromomethyl group. This compound is typically a colorless to pale yellow liquid with a distinctive odor. It is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the bromine atom, which can be replaced by various nucleophiles. The chlorine substituents contribute to its electron-withdrawing properties, influencing its chemical behavior and reactivity. 2,6-Dichlorobenzyl bromide is often utilized in organic synthesis, particularly in the preparation of other chemical compounds, including pharmaceuticals and agrochemicals. It is important to handle this substance with care, as it may pose health risks upon exposure, including skin and respiratory irritation. Proper safety measures, including the use of personal protective equipment and working in a well-ventilated area, are essential when working with this compound.

Formula: C₇H₅BrCl₂

InChI: InChI=1S/C7H5BrCl2/c8-4-5-6(9)2-1-3-7(5)10/h1-3H,4H2

InChI key: InChIKey=PDFGFQUSSYSWNI-UHFFFAOYSA-N

SMILES: C(Br)C1=C(Cl)C=CC=C1Cl

Synonyms:

• 1-Bromomethyl-2,6-dichlorobenzene
• 2,6-Dichloro-α-bromotoluene
• 2-(Bromomethyl)-1,3-Dichlorobenzene
• A-Bromo-2,6-Dichlorotoluene
• Benzene, 2-(bromomethyl)-1,3-dichloro-
• NSC 93898
• Toluene, α-bromo-2,6-dichloro-
• alpha-Bromo-2,6-dichlorotoluene
• 2,6-Dichlorobenzyl bromide

2,6-Dichlorobenzyl bromide

CAS: 20443-98-5

Formula: C₇H₅BrCl₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.9246

Ref: IN-DA003B5K

α-Bromo-2,6-dichlorotoluene (2,6-dichlorobenzyl bromide)

CAS: 20443-98-5

Formula: C₇H₅BrCl₂

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 239.93

Ref: 7W-GK3566

2-(Bromomethyl)-1,3-dichlorobenzene

CAS: 20443-98-5

Formula: C₇H₅BrCl₂

Purity: 97.0%

Color and Shape: Solid, Crystalline

Molecular weight: 239.92

Ref: 10-F050219

2,6-Dichlorobenzyl bromide

CAS: 20443-98-5

2,6-Dichlorobenzyl bromide

Formula: C₇H₅BrCl₂

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 239.92g/mol

Ref: 54-OR2114

2,6-Dichlorobenzyl Bromide

Controlled Product

CAS: 20443-98-5

Applications 2,6-Dichlorobenzyl Bromide is used in the preparation of potent epoxide hydrolase inhibitors. Has shown thus far to relieve hypotension in lipopolysaccharide deficient murine models. As well they have been used in the synthesis of anti-HIV drugs based on diaryltriazine (DATA) analogues.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hwang, S. et al.: J. Med. Chem., 50, 3825 (2007); Ludovici, D. et al.: Bioorg. Med. Chem. Lett., 11, 2229 (2001);

Formula: C₇H₅BrCl₂

Color and Shape: Neat

Molecular weight: 239.92

Ref: TR-D432300

2,6-Dichloro benzyl bromide

CAS: 20443-98-5

2,6-Dichlorobenzyl bromide is a pharmacokinetic solvent that is used to dissolve amines. It is an organic solvent that is soluble in water and slightly soluble in ethanol. 2,6-Dichlorobenzyl bromide reacts with Grignard reagents to form acyl halides. This reaction system is called the Friedel-Crafts acylation. 2,6-Dichlorobenzyl bromide can be used for the modification of molecules by alkylation or for the synthesis of neurotensin receptor antagonists or other drugs. There are genotoxic impurities that may be present in this drug, so it should not be used in pregnant women or children because it may cause birth defects or cancer.

Formula: C₇H₅BrCl₂

Purity: Min. 95%

Molecular weight: 239.92 g/mol

Ref: 3D-FD12581

2,6-Dichlorobenzyl Bromide

CAS: 20443-98-5

Formula: C₇H₅BrCl₂

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 239.92

Ref: 3B-D1749