CAS 20445-31-2: (R)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid

Description: (R)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, with the CAS number 20445-31-2, is a chiral compound characterized by its unique functional groups and stereochemistry. This substance features a methoxy group and a trifluoromethyl group attached to a phenylacetic acid backbone, contributing to its distinct chemical properties. The presence of the trifluoromethyl group enhances the lipophilicity and metabolic stability of the compound, making it of interest in medicinal chemistry. The methoxy group can influence the compound's reactivity and solubility. As a chiral molecule, it exists in two enantiomeric forms, with the (R)-configuration often being more biologically active. This compound may exhibit specific interactions with biological targets, making it relevant in drug design and development. Its synthesis typically involves asymmetric methods to ensure the desired stereochemistry is achieved. Overall, (R)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid is notable for its potential applications in pharmaceuticals and its role in studying chiral compounds in organic chemistry.

Formula: C₁₀H₉F₃O₃

InChI: InChI=1S/C10H9F3O3/c1-16-9(8(14)15,10(11,12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,14,15)/t9-/m1/s1

InChI key: InChIKey=JJYKJUXBWFATTE-SECBINFHSA-N

SMILES: O=C(O)C(OC)(C=1C=CC=CC1)C(F)(F)F

Synonyms:

• (+)-3,3,3-Trifluoro-2-methoxy-2-phenylpropionic acid
• (+)-Mosher's acid
• (+)-Moshers acid
• (+)-Moshers acid~(+)-MTPA
• (+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid
• (+)Mtpa
• (2R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
• (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
• (R)-(+)-3,3,3-Trifluoro-2-phenyl-2-methoxypropanoic acid
• (R)-(+)-MTPA acid
• (R)-(+)-Mosher acid
• (R)-(+)-Mosher's acid
• (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid
• (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
• (R)-2-Methoxy-2-(trifluoromethylphenylacetic acid
• (R)-2-Methoxy-2-phenyl-2-(trifluoromethyl)ethanoic acid
• (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
• (R)-Mtpa
• (R)-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid
• (R)-α-Methoxy-α-(trifluoromethyl)phenylethanoic acid
• (R)-α-Methoxy-α-trifluoromethylphenylacetic acid
• (αR)-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid
• Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (R)-
• Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (αR)-
• Hydratropic acid, β,β,β-trifluoro-α-methoxy-, (+)-
• R-Mtpa-Oh

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving]

CAS: 20445-31-2

• Formula: C₁₀H₉F₃O₃
• Purity: >98.0%(GC)(T)
• Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid
• Molecular weight: 234.17

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, 99%

CAS: 20445-31-2

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is widely used reagent for determination of optical purities of alcohols and amines …

• Formula: C₁₀H₉F₃O₃
• Purity: 99%
• Color and Shape: Colorless to white to pale yellow, Crystals or powder or crystalline powder or fused solid or clear viscous liquid or low melting solid
• Molecular weight: 234.17

Benzeneacetic acid, a-methoxy-a-(trifluoromethyl)-, (aR)-

CAS: 20445-31-2

• Formula: C₁₀H₉F₃O₃
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 234.1719

(2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid

CAS: 20445-31-2

• Formula: C₁₀H₉F₃O₃
• Purity: 99%
• Color and Shape: clear. almost colourless low melting solid
• Molecular weight: 234.17g/mol

(+)-a-Methoxy-a-(trifluoromethyl)phenylacetic acid

CAS: 20445-31-2

• Purity: 98.0%
• Color and Shape: Low Melting Solid
• Molecular weight: 234.174

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, 99%

CAS: 20445-31-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₀H₉F₃O₃
• Purity: 99%
• Color and Shape: Clear colorless to light yellow, Viscous liquid or low melting solid
• Molecular weight: 234.17

(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid

CAS: 20445-31-2

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid is a phenyl compound that has been shown to inhibit the growth of …

• Formula: C₁₀H₉F₃O₃
• Purity: Min. 95%
• Molecular weight: 234.17 g/mol