CAS 20445-33-4
:(S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride
Description:
(S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride, with the CAS number 20445-33-4, is an organic compound characterized by its unique functional groups and stereochemistry. This compound features a phenylacetyl chloride structure, which includes an acetyl chloride moiety attached to a phenyl ring that is further substituted with a methoxy group and a trifluoromethyl group. The presence of the trifluoromethyl group imparts significant electronegativity and lipophilicity, enhancing the compound's reactivity and potential applications in medicinal chemistry and organic synthesis. The methoxy group contributes to the compound's solubility and can influence its reactivity in nucleophilic substitution reactions. As a chiral molecule, it exhibits optical activity, which can be crucial in the development of enantioselective synthesis processes. Overall, this compound is of interest in various chemical applications, particularly in the synthesis of pharmaceuticals and agrochemicals, due to its distinctive structural features and reactivity profile.
Formula:C10H8ClF3O2
InChI:InChI=1/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m1/s1
SMILES:CO[C@](c1ccccc1)(C(=O)Cl)C(F)(F)F
Synonyms:- 3,3,3-Trifluoro-2-Methoxy-2-Phenylpropanoyl Chloride
- (2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
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Found 7 products.
(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L) [for Determination of the optical purity of Alcohols and Amines]
CAS:Formula:C10H8ClF3O2Purity:min. 99.0 ee%(GC)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:252.62(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines]
CAS:Formula:C10H8ClF3O2Purity:>98.0%(GC)(T)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:252.62(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 98+%
CAS:<p>(S)-(+)--Methoxy--(trifluoromethyl)phenylacetyl chloride is used in the preparation of natural products and pheromones. It is also employed as a derivatization enantiomeric purity reagent used for the determination of enantiomeric purity of alcohol and amines by gas chromatography. This Thermo Scie</p>Formula:C10H8ClF3O2Purity:98+%Color and Shape:Clear colorless, Liquid or viscous liquidMolecular weight:252.62(S)-(+)-α-Methoxy-α-trifluoromethylphenylacetylchloride
CAS:Formula:C10H8ClF3O2Purity:97%Color and Shape:LiquidMolecular weight:252.6175(2S)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride
CAS:(2S)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chlorideFormula:C10H8ClF3O2Purity:99%Color and Shape: clear. almost colourless liquidMolecular weight:252.62g/mol(S)-(+)-a-Methoxy-a-trifluoromethylphenylacetyl chloride
CAS:Formula:C10H8ClF3O2Purity:98.0%Color and Shape:Clear Liquid or Viscous LiquidMolecular weight:252.62S-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid chloride
CAS:<p>S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride is an optical, amide, and epoxidation derivatizing agent that is used to chiralify amines. It is a liquid at room temperature with a molecular weight of 123.87 g/mol. This chemical reacts with alcohols to form esters, which can be identified by their different retention times in chromatography. It also reacts with hydroxyl groups to form ethers and esters, as well as hydroxyls on other molecules such as amino acids, peptides, and proteins. S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride has been used for the synthesis of bisoprolol from metoprolol and triethylphosphite.</p>Formula:C10H8ClF3O2Purity:Min. 95%Molecular weight:252.62 g/mol





