CAS 20445-33-4

(S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride

Description:

(S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride, with the CAS number 20445-33-4, is an organic compound characterized by its unique functional groups and stereochemistry. This compound features a phenylacetyl chloride structure, which includes an acetyl chloride moiety attached to a phenyl ring that is further substituted with a methoxy group and a trifluoromethyl group. The presence of the trifluoromethyl group imparts significant electronegativity and lipophilicity, enhancing the compound's reactivity and potential applications in medicinal chemistry and organic synthesis. The methoxy group contributes to the compound's solubility and can influence its reactivity in nucleophilic substitution reactions. As a chiral molecule, it exhibits optical activity, which can be crucial in the development of enantioselective synthesis processes. Overall, this compound is of interest in various chemical applications, particularly in the synthesis of pharmaceuticals and agrochemicals, due to its distinctive structural features and reactivity profile.

Formula: C₁₀H₈ClF₃O₂

InChI: InChI=1/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m1/s1

SMILES: CO[C@](c1ccccc1)(C(=O)Cl)C(F)(F)F

Synonyms:

• 3,3,3-Trifluoro-2-Methoxy-2-Phenylpropanoyl Chloride
• (2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride

(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L) [for Determination of the optical purity of Alcohols and Amines]

CAS: 20445-33-4

Formula: C₁₀H₈ClF₃O₂

Purity: min. 99.0 ee%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 252.62

Ref: 3B-M2214

(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines]

CAS: 20445-33-4

Formula: C₁₀H₈ClF₃O₂

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 252.62

Ref: 3B-M1103

(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 98+%

CAS: 20445-33-4

(S)-(+)--Methoxy--(trifluoromethyl)phenylacetyl chloride is used in the preparation of natural products and pheromones. It is also employed as a derivatization enantiomeric purity reagent used for the determination of enantiomeric purity of alcohol and amines by gas chromatography. This Thermo Scie

Formula: C₁₀H₈ClF₃O₂

Purity: 98+%

Color and Shape: Clear colorless, Liquid or viscous liquid

Molecular weight: 252.62

Ref: 02-L14332

(S)-(+)-α-Methoxy-α-trifluoromethylphenylacetylchloride

CAS: 20445-33-4

Formula: C₁₀H₈ClF₃O₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 252.6175

Ref: IN-DA0032G7

(2S)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride

CAS: 20445-33-4

(2S)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride

Formula: C₁₀H₈ClF₃O₂

Purity: 99%

Color and Shape: clear. almost colourless liquid

Molecular weight: 252.62g/mol

Ref: 54-PC5063J

(S)-(+)-a-Methoxy-a-trifluoromethylphenylacetyl chloride

CAS: 20445-33-4

Formula: C₁₀H₈ClF₃O₂

Purity: 98.0%

Color and Shape: Clear Liquid or Viscous Liquid

Molecular weight: 252.62

Ref: 10-F009427

S-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid chloride

CAS: 20445-33-4

S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride is an optical, amide, and epoxidation derivatizing agent that is used to chiralify amines. It is a liquid at room temperature with a molecular weight of 123.87 g/mol. This chemical reacts with alcohols to form esters, which can be identified by their different retention times in chromatography. It also reacts with hydroxyl groups to form ethers and esters, as well as hydroxyls on other molecules such as amino acids, peptides, and proteins. S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride has been used for the synthesis of bisoprolol from metoprolol and triethylphosphite.

Formula: C₁₀H₈ClF₃O₂

Purity: Min. 95%

Molecular weight: 252.62 g/mol

Ref: 3D-FM64036