CAS 20448-79-7

2-aminobicyclo[2.2.1]heptane-2-carboxylic acid

Description:

2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid, also known as norbornane-2-carboxylic acid, is a bicyclic compound characterized by its unique bicyclic structure, which consists of a seven-membered ring system. This compound features an amino group (-NH2) and a carboxylic acid group (-COOH) attached to the same carbon atom, making it an amino acid derivative. It is typically a white to off-white solid at room temperature and is soluble in water due to the presence of the carboxylic acid group, which can ionize to form a carboxylate anion. The bicyclic structure contributes to its rigidity and can influence its reactivity and interactions with biological systems. This compound is of interest in various fields, including medicinal chemistry and organic synthesis, due to its potential applications in drug development and as a building block for more complex molecules. Its CAS number, 20448-79-7, is used for identification in chemical databases and regulatory contexts.

Formula: C₈H₁₃NO₂

InChI: InChI=1/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)

SMILES: C1CC2CC1CC2(C(=O)O)N

Synonyms:

• Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-
• 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid

Bicyclo[2.2.1]heptane-2-carboxylic acid, 2-amino-

CAS: 20448-79-7

Formula: C₈H₁₃NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 155.1943

Ref: IN-DA0029IU

LAT1-IN-1

CAS: 20448-79-7

LAT1-IN-1 (BCH) is a selective and competitive inhibitor of L-type amino acid transporter protein 1 (LAT1). LAT1-IN-1 has antitumor activity. Cost-effective and quality-assured.

Formula: C₈H₁₃NO₂

Purity: 99.94% - ≥98%

Color and Shape: Solid

Molecular weight: 155.19

Ref: TM-T11820

LAT1-IN-1

CAS: 20448-79-7

LAT1-IN-1

Purity: ≥98%

Molecular weight: 155.19g/mol

Ref: 54-BUP14353

2-Amino-2-norbornanecarboxylic acid

CAS: 20448-79-7

Formula: C₈H₁₃NO₂

Purity: ≥ 97.0%

Color and Shape: White to brown powder

Molecular weight: 155.19

Ref: 7W-GM9754

2-Aminobicyclo[2.2.1]Heptane-2-Carboxylic Acid

CAS: 20448-79-7

2-Aminobicyclo[2.2.1]Heptane-2-Carboxylic Acid

Purity: 95%

Molecular weight: 155.19g/mol

Ref: 54-OR1025836

2-Amino-2-norbornanecarboxylic Acid

Controlled Product

CAS: 20448-79-7

Applications 2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells
References Ohshima, Y., et al.: Cancer Science, 107, 1499 (206); Huttunen, K. M., et al.: J. Med. Chem., 59, 5740 (2016)

Formula: C₈H₁₃NO₂

Color and Shape: White To Off-White

Molecular weight: 155.19

Ref: TR-A619050

Bicyclo[2.2.1]heptane-2-carboxylic acid, 2-amino-

CAS: 20448-79-7

Purity: 95%

Molecular weight: 155.1970062

Ref: 10-F865819