CAS 2047-49-6

5-Nitronicotinic acid

Description:

5-Nitronicotinic acid, with the CAS number 2047-49-6, is a chemical compound that belongs to the class of nitro-substituted pyridine carboxylic acids. It features a pyridine ring with a nitro group (-NO2) and a carboxylic acid group (-COOH) attached to the fifth and first positions, respectively. This compound is typically characterized by its crystalline solid form, which is soluble in polar solvents such as water and alcohols. The presence of both the nitro and carboxylic acid functional groups contributes to its acidic properties and potential reactivity. 5-Nitronicotinic acid may exhibit biological activity, making it of interest in pharmaceutical research, particularly in the development of compounds with antimicrobial or anti-inflammatory properties. Additionally, its structural features allow for various chemical modifications, which can lead to the synthesis of derivatives with enhanced or altered biological activities. As with many nitro compounds, care should be taken regarding its handling and storage due to potential toxicity and environmental concerns.

Formula: C₆H₄N₂O₄

InChI: InChI=1/C6H4N2O4/c9-6(10)4-1-5(8(11)12)3-7-2-4/h1-3H,(H,9,10)

SMILES: c1c(cncc1N(=O)=O)C(=O)O

Synonyms:

• 3-Pyridinecarboxylic Acid, 5-Nitro-
• 5-Nitropyridine-3-Carboxylic Acid

3-Pyridinecarboxylic acid, 5-nitro-

CAS: 2047-49-6

Formula: C₆H₄N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 168.1070

Ref: IN-DA0029NP

Nicotinic Acid EP Impurity F (5-Nitronicotinic Acid)

CAS: 2047-49-6

Formula: C₆H₄N₂O₄

Color and Shape: Yellow Solid

Molecular weight: 168.11

Ref: 4Z-N-056003

5-Nitronicotinic acid

CAS: 2047-49-6

5-Nitronicotinic acid

Formula: C₆H₄N₂O₄

Purity: 95%

Color and Shape: yellow solid

Molecular weight: 168.11g/mol

Ref: 54-OR8897

5-Nitro Nicotinic Acid

Controlled Product

CAS: 2047-49-6

Applications An intermediate in the synthesis of nicotinamide with potential anticoccidial activity.
References Morisawa, Y. et al.: J. Med. Chem., 20, 129 (1977);

Formula: C₆H₄N₂O₄

Color and Shape: Neat

Molecular weight: 168.11

Ref: TR-N496870

5-Nitronicotinic acid

CAS: 2047-49-6

Formula: C₆H₄N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 168.108

Ref: 10-F223348

Nicotinic Acid EP Impurity F

CAS: 2047-49-6

Formula: C₆H₄N₂O₄

Molecular weight: 168.11

Ref: ST-EA-CP-N50004

5-Nitro nicotinic acid

CAS: 2047-49-6

5-Nitro nicotinic acid is a drug that has been synthesized in the laboratory. It is a white crystalline solid with a molecular weight of 201.18, and it has the chemical formula of C6H5NO2. 5-Nitro nicotinic acid is an antitubercular drug that inhibits Mycobacterium tuberculosis and Mycobacterium avium complex without inhibiting other human cells. It also inhibits the growth of bacteria that are resistant to aminoglycosides (e.g., Pbtz169). This drug binds to the enzyme NADH dehydrogenase, which leads to inhibition of bacterial respiration and ATP synthesis. 5-Nitro nicotinic acid also has antimycobacterial activity against mycobacteria by forming nitric oxide radicals (NO) through hydrogen peroxide oxidation, which react with cellular components such as DNA and proteins.

Formula: C₆H₄N₂O₄

Purity: Min. 95%

Molecular weight: 168.11 g/mol

Ref: 3D-FN26238