CAS 204777-78-6

N~6~-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

Description:

N~6~-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine, with CAS number 204777-78-6, is a synthetic amino acid derivative that features a complex structure characterized by multiple functional groups. This compound includes a lysine backbone, which is an essential amino acid known for its role in protein synthesis and various metabolic processes. The presence of the fluorenylmethoxycarbonyl (Fmoc) group indicates its application in peptide synthesis, particularly in solid-phase peptide synthesis, where it serves as a protective group for the amino functionality. The cyclohexylidene moiety contributes to the compound's steric properties and may influence its reactivity and interaction with biological targets. Additionally, the presence of the dimethyl and dioxo substituents suggests potential for unique chemical behavior, possibly enhancing its stability or solubility in various solvents. Overall, this compound's intricate structure and functional groups make it a valuable candidate for research in biochemistry and medicinal chemistry.

Formula: C₃₄H₄₂N₂O₆

InChI: InChI=1/C34H42N2O6/c1-21(2)17-28(31-29(37)18-34(3,4)19-30(31)38)35-16-10-9-15-27(32(39)40)36-33(41)42-20-26-24-13-7-5-11-22(24)23-12-6-8-14-25(23)26/h5-8,11-14,21,26-27,35H,9-10,15-20H2,1-4H3,(H,36,41)(H,39,40)/t27-/m0/s1

SMILES: CC(C)CC(=C1C(=O)CC(C)(C)CC1=O)NCCCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-Lys(ivDde)-OH
• Fmoc-Lys(Ddiv)-OH

Fmoc-Lys(ivDde)-OH

CAS: 204777-78-6

The ivDde protective group possesses higher orthogonality regarding Boc and Fmoc in comparison to Dde.

Formula: C₃₄H₄₂N₂O₆

Purity: 99.3%

Color and Shape: Light Yellow

Molecular weight: 574.72

Ref: 01-4034540

L-Lysine, N6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 204777-78-6

Formula: C₃₄H₄₂N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 574.7071

Ref: IN-DA0029OH

Fmoc-Lys(Ddiv)-OH

CAS: 204777-78-6

Purity: ≥ 95.0%

Color and Shape: White to light yellow or beige powder

Molecular weight: 574.71

Ref: 7W-GM1716

Fmoc-L-Lys(ivDde)-OH

CAS: 204777-78-6

Fmoc-L-Lys(ivDde)-OH

Purity: 99%

Color and Shape: White Powder

Molecular weight: 574.71g/mol

Ref: 54-BIF1009

Fmoc-Lys(ivDde)-OH

CAS: 204777-78-6

Formula: C₃₄H₄₂N₂O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 574.72

Ref: 3B-F1321

Fmoc-Lys(ivDde)-OH

CAS: 204777-78-6

M06254 - Fmoc-Lys(ivDde)-OH

Formula: C₃₄H₄₂N₂O₆

Purity: 95%

Color and Shape: White powder

Molecular weight: 574.718

Ref: 10-M06254

N-α-Fmoc-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-lysine

CAS: 204777-78-6

N-alpha-Fmoc-Nepsilon-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-lysine is a synthetic peptide that is used in the study of prostate cancer. It binds to tumor cells and may be used as a radiotracer for imaging. Nalpha Fmoc Nepsilon 1 (4,4 dimethyl 2,6 dioxocyclohexylidene) 3 methylbutyl L Lysine has been shown to bind to an antigen on prostate cancer cells and stimulate their uptake by macrophages in vitro. This synthetic peptide also inhibits cell proliferation and induces apoptosis in prostate cancer cells. Clinical data suggests that this compound is safe for use in humans. The synthesis of this compound requires the formation of a disulfide bond between the two cysteine residues.

Formula: C₃₄H₄₂N₂O₆

Purity: Min. 95%

Molecular weight: 574.71 g/mol

Ref: 3D-FF49068