CAS 204970-99-0

Benzamide, 4-[[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]methylamino]-N-propyl-, hydrochloride (1:1)

Description:

Benzamide, 4-[[[1S]-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]methylamino]-N-propyl-, hydrochloride (1:1), with CAS number 204970-99-0, is a chemical compound characterized by its complex structure, which includes a benzamide moiety and a propyl group linked to a chiral center. This compound features a pyrrolidine ring that contributes to its pharmacological properties, often associated with interactions in the central nervous system. The presence of the hydroxyl group enhances its solubility and potential biological activity. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for various applications in medicinal chemistry. The stereochemistry indicated by the (1S) and (3S) designations suggests specific spatial arrangements that can significantly influence the compound's biological activity and receptor interactions. Overall, this compound is of interest in research and development, particularly in the fields of neuropharmacology and drug design.

Formula: C₂₃H₃₁N₃O₂·ClH

InChI: InChI=1S/C23H31N3O2.ClH/c1-3-14-24-23(28)19-9-11-20(12-10-19)25(2)22(18-7-5-4-6-8-18)17-26-15-13-21(27)16-26;/h4-12,21-22,27H,3,13-17H2,1-2H3,(H,24,28);1H/t21-,22+;/m0./s1

InChI key: InChIKey=UIDQSFVIAHCPLD-UMIAIAFLSA-N

SMILES: [C@@H](N(C)C1=CC=C(C(NCCC)=O)C=C1)(CN2C[C@@H](O)CC2)C3=CC=CC=C3.Cl

Synonyms:

• Benzamide, 4-[[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]methylamino]-N-propyl-, hydrochloride (1:1)
• Benzamide, 4-[[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]methylamino]-N-propyl-, monohydrochloride
• Benzamide, 4-[[2-(3-hydroxy-1-pyrrolidinyl)-1-phenylethyl]methylamino]-N-propyl-, monohydrochloride, [S-(R*,R*)]-

CJ-15161 hydrochloride

CAS: 204970-99-0

CJ-15161 hydrochloride is the salt form of CJ-15161 (free base), an opioid κ-receptor agonist, is undergoing development with Pfizer as an analgesic agent.

Formula: C₂₃H₃₂ClN₃O₂

Color and Shape: Solid

Molecular weight: 417.978

Ref: TM-T69960