CAS 20503-40-6

6-Amino-1,1-dioxobenzo[b]thiophene

Description:

6-Amino-1,1-dioxobenzo[b]thiophene is a heterocyclic compound characterized by the presence of a thiophene ring fused to a benzene structure, along with an amino group and a dioxo functional group. This compound typically exhibits a pale yellow to light brown appearance and is soluble in polar organic solvents. The presence of the amino group suggests potential for hydrogen bonding, which can influence its reactivity and interactions with other molecules. The dioxo functionality indicates that it may participate in redox reactions, making it of interest in various chemical applications, including organic synthesis and potentially in medicinal chemistry. Its unique structure allows for various substitution reactions, which can be exploited to create derivatives with tailored properties. Additionally, compounds of this type may exhibit biological activity, warranting further investigation into their pharmacological potential. As with many heterocycles, the stability and reactivity of 6-Amino-1,1-dioxobenzo[b]thiophene can be influenced by environmental factors such as pH and temperature.

Formula: C₈H₇NO₂S

InChI: InChI=1S/C8H7NO2S/c9-7-2-1-6-3-4-12(10,11)8(6)5-7/h1-5H,9H2

InChI key: InChIKey=KRUCRVZSHWOMHC-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(C=C1)=CC=C(N)C2

Synonyms:

• (1,1-Dioxobenzothiophen-6-yl)amine
• 1,1-Dioxo-1-benzothiophen-6-amine
• 1,1-Dioxo-1H-benzo[b]thiophen-6-ylamine
• 1-Benzothiophen-6-Amine 1,1-Dioxide
• 6-Amino-1,1-dioxobenzo[b]thiophene
• 6-Aminobenzo[b]thiophene-1,1-dioxide
• 6-Aminobenzothiophene-1,1-dioxide
• Benzo[b]thiophen-6-amine, 1,1-dioxide

Benzo[b]thiophen-6-amine, 1,1-dioxide

CAS: 20503-40-6

Formula: C₈H₇NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 181.2117

Ref: IN-DA0029TJ

6-Aminobenzo[b]thiophene 1,1-dioxide

CAS: 20503-40-6

6-Aminobenzo[b]thiophene 1,1-dioxide

Formula: C₈H₇NO₂S

Purity: 97%

Color and Shape: light yellow to yellow solid

Molecular weight: 181.21167g/mol

Ref: 54-OR26007

6-Aminobenzo[b]thiophene 1,1-dioxide

CAS: 20503-40-6

Formula: C₈H₇NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 181.21

Ref: 10-F324195

1,1-Dioxido-1-benzothien-6-ylamine

CAS: 20503-40-6

1,1-Dioxido-1-benzothien-6-ylamine is a cytotoxic drug that inhibits the synthesis of DNA and RNA in cancer cells. It is synthesized from benzo[c]thiophene-2,5-dione by oxidation with nitric acid to give the corresponding dioxido compound. The synthesized product has high lipophilicity (log P = 2.2) and a reactive hydroxy group that can undergo modifications such as esterification or alkylation. 1,1-Dioxido-1-benzothien-6-ylamine shows potent antitumor activity against solid tumours and high lipophilicity that enables it to cross the blood brain barrier very easily. It also induces apoptosis in tumour cells by binding to nucleic acids and inhibiting their synthesis. This drug is cytotoxic at nanomolar concentrations and has been shown to be effective against lung

Formula: C₈H₇NO₂S

Purity: Min. 95%

Molecular weight: 181.21 g/mol

Ref: 3D-VAA50340