CAS 205110-48-1

Cethromycin

Description:

Cethromycin is a synthetic antibiotic belonging to the class of macrolides, specifically designed to combat bacterial infections. It is characterized by its broad-spectrum activity against various Gram-positive and some Gram-negative bacteria, making it effective in treating respiratory tract infections, skin infections, and other bacterial diseases. Cethromycin works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. Its mechanism of action involves binding to the 50S ribosomal subunit, similar to other macrolides, but it has a unique structure that enhances its efficacy against certain resistant strains. The compound is typically administered orally and has a favorable pharmacokinetic profile, allowing for effective tissue penetration. Additionally, Cethromycin has been studied for its potential anti-inflammatory properties, which may contribute to its therapeutic effects in respiratory conditions. However, like all antibiotics, its use should be guided by susceptibility patterns to minimize the risk of resistance development.

Formula: C₄₂H₅₉N₃O₁₀

InChI: InChI=1S/C42H59N3O10/c1-11-32-42(8)36(44-40(50)55-42)25(4)33(46)23(2)21-41(7,51-18-14-15-28-20-29-16-12-13-17-30(29)43-22-28)37(26(5)34(47)27(6)38(49)53-32)54-39-35(48)31(45(9)10)19-24(3)52-39/h12-17,20,22-27,31-32,35-37,39,48H,11,18-19,21H2,1-10H3,(H,44,50)/t23-,24-,25+,26+,27-,31+,32-,35-,36-,37-,39+,41-,42-/m1/s1

InChI key: InChIKey=PENDGIOBPJLVBT-AMXFZXBBSA-N

SMILES: C[C@@]12[C@](NC(=O)O1)([C@@H](C)C(=O)[C@H](C)C[C@](OCC=CC3=CC4=C(N=C3)C=CC=C4)(C)[C@H](O[C@H]5[C@H](O)[C@@H](N(C)C)C[C@@H](C)O5)[C@@H](C)C(=O)[C@@H](C)C(=O)O[C@@H]2CC)[H]

Synonyms:

• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-3a,7,9,11,13,15-hexamethyl-11-[[3-(3-quinolinyl)-2-propenyl]oxy]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-<span class="text-smallcaps">D</span>-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone
• (3aS,4S,7R,9R,10R,11R,13R,15S,15aR)-4-ethyl-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-11-{[(2E)-3-(quinolin-3-yl)prop-2-en-1-yl]oxy}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside
• 2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 4-ethyloctahydro-3a,7,9,11,13,15-hexamethyl-11-[[3-(3-quinolinyl)-2-propenyl]oxy]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-<span class="text-smallcaps">D</span>-xylo-hexopyranosyl]oxy]-, (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-
• A 195773
• Abbott-195773
• Abt-773
• Cethromycin
• 2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 4-ethyloctahydro-3a,7,9,11,13,15-hexamethyl-11-[[3-(3-quinolinyl)-2-propenyl]oxy]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-
• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-3a,7,9,11,13,15-hexamethyl-11-[[3-(3-quinolinyl)-2-propenyl]oxy]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone

Cethromycin

CAS: 205110-48-1

Cethromycin (ABT-773) is an antibiotic of ketolide.

Formula: C₄₂H₅₉N₃O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 765.93

Ref: TM-T14934

Restanza

CAS: 205110-48-1

Restanza is an antibiotic, which is derived from novel sources to combat resistant bacterial strains. It functions through the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively halting the translation process. This mechanism of action is designed to disrupt the proliferation of bacteria, making it a powerful tool in the fight against various infections.

Formula: C₄₂H₅₉N₃O₁₀

Purity: Min. 95%

Molecular weight: 765.9 g/mol

Ref: 3D-FIA11048