CAS 205121-37-5

Uridine,2'-O-(6-aminohexyl)-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-

Description:

Uridine, 2'-O-(6-aminohexyl)-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl- is a modified nucleoside that features a uridine base with specific chemical modifications enhancing its properties. The presence of a 6-aminohexyl group at the 2' position contributes to its solubility and potential for biological interactions, while the 5'-O-[bis(4-methoxyphenyl)phenylmethyl] modification may enhance its stability and affinity for target molecules. The additional methyl group at the 5' position can influence the nucleoside's reactivity and binding characteristics. This compound is of interest in biochemical research, particularly in studies involving nucleic acid interactions, drug design, and the development of therapeutic agents. Its unique structure may allow for specific interactions with enzymes or receptors, making it a valuable tool in molecular biology and medicinal chemistry. As with many modified nucleosides, its characteristics, including solubility, stability, and biological activity, can vary significantly based on the specific modifications present.

Formula: C₃₇H₄₅N₃O₈

5'-O-DMT-2'-O-hexylamino-5-methyluridine

CAS: 205121-37-5

5'-O-DMT-2'-O-hexylamino-5-methyluridine is a nucleoside analog that is used in cancer treatment. It is synthesized by the chemical modification of uridine, which is converted to 5'-O-DMT-2'-O-hexylamino-5-methyluridine by reacting with 2',3'-dideoxyadenosine and 5,6,7,8,-tetrahydroisoquinoline. The monophosphate form of 5'-O-DMT-2'-O-hexylamino-5-methyluridine may be converted to the diphosphate form by phosphorylation with ATP. In addition to its anticancer effects, 5'-O-DMT-2'-O-hexylamino-5-methyluridine has antiviral and antiretroviral effects due to its inhibition of viral DNA synthesis.

Formula: C₃₇H₄₅N₃O₈

Purity: Min. 95%

Molecular weight: 659.79 g/mol

Ref: 3D-ND08520