CAS 205393-21-1: Bortezomib intermediates II

Description: Bortezomib intermediates II, with the CAS number 205393-21-1, is a chemical compound that serves as an intermediate in the synthesis of the proteasome inhibitor bortezomib, which is used in the treatment of multiple myeloma and certain types of lymphoma. This compound typically exhibits characteristics common to organic intermediates, such as being a solid at room temperature, with potential solubility in organic solvents. Its molecular structure includes functional groups that facilitate further chemical reactions, making it a crucial step in the synthetic pathway of bortezomib. The compound may possess specific reactivity patterns, including the ability to undergo nucleophilic substitutions or coupling reactions, which are essential for the formation of the final therapeutic agent. Safety data sheets would indicate handling precautions, as intermediates can often be hazardous. Overall, Bortezomib intermediates II plays a vital role in pharmaceutical chemistry, contributing to the development of effective cancer treatments.

Synonyms:

• N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]
• (alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamide hydrochloride
• Bortezomib Intermediate II

Benzenepropanamide, α-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-, hydrochloride (1:1), (αS)-

CAS: 205393-21-1

• Formula: C₂₄H₃₈BClN₂O₃
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 448.83412

Bortezomib Impurity 54 HCl

CAS: 205393-21-1

• Formula: C₂₄H₃₇BN₂O₃·HCl
• Molecular weight: 412.38 36.46

(alphaS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamide Hydrochloride (Bortezomib Intermediate II)

CAS: 205393-21-1

• Formula: C₂₄H₃₇BN₂O₃·ClH
• Color and Shape: Neat
• Molecular weight: 448.8341

(alphaS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride

CAS: 205393-21-1

Applications (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride is a Bortezomib (B675700) intermediate which is used in the evaluation of …

• Formula: C₂₄H₃₇BN₂O₃·ClH
• Color and Shape: Neat
• Molecular weight: 448.8341

(alphaS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]ben zenepropanamideHydrochloride

CAS: 205393-21-1

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• Formula: C₂₄H₃₈BClN₂O₃
• Purity: Min. 95%
• Molecular weight: 448.83 g/mol