CAS 205445-52-9

N-[(1,1-Dimethylethoxy)carbonyl]-3,5-difluoro-L-phenylalanine

Description:

N-[(1,1-Dimethylethoxy)carbonyl]-3,5-difluoro-L-phenylalanine is a synthetic amino acid derivative characterized by the presence of a fluorinated phenylalanine structure. This compound features a carbonyl group attached to a 1,1-dimethylethoxy group, which enhances its lipophilicity and stability. The difluorination at the 3 and 5 positions of the phenyl ring introduces unique electronic properties, potentially influencing its reactivity and interaction with biological systems. This compound is typically used in pharmaceutical research, particularly in the development of peptide-based drugs, due to its ability to modify peptide properties such as solubility and bioavailability. Its molecular structure allows for specific interactions with biological targets, making it a valuable tool in medicinal chemistry. Additionally, the presence of the dimethylethoxy group may provide steric hindrance, which can affect the conformation and activity of peptides in which it is incorporated. Overall, this compound exemplifies the strategic design of amino acid derivatives for enhanced therapeutic efficacy.

Formula: C₁₄H₁₇F₂NO₄

InChI: InChI=1S/C14H17F2NO4/c1-14(2,3)21-13(20)17-11(12(18)19)6-8-4-9(15)7-10(16)5-8/h4-5,7,11H,6H2,1-3H3,(H,17,20)(H,18,19)/t11-/m0/s1

InChI key: InChIKey=CZBNUDVCRKSYDG-NSHDSACASA-N

SMILES: C([C@H](NC(OC(C)(C)C)=O)C(O)=O)C1=CC(F)=CC(F)=C1

Synonyms:

• (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,5-difluorophenyl)propanoic acid
• (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,5-difluorophenyl)propionic acid
• (S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,5-difluorophenyl)propanoic acid
• (S)-N-Boc-3,5-difluorophenylalanine
• 2-(S)-[(tert-Butoxycarbonyl)amino]-3-(3,5-difluorophenyl)propionic acid
• <span class="text-smallcaps">L</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-3,5-difluoro-
• Boc-3,5-Difluoro-L-phenylalanine
• Boc-L-3,5-Difluorophe
• Boc-Phe(3,5-DiF)-OH
• N-(tert-Butoxycarbonyl)-3,5-difluoro-<span class="text-smallcaps">L</span>-phenylalanine
• N-Boc-<span class="text-smallcaps">L</span>-3,5-difluorophenylalanine
• N-[(1,1-Dimethylethoxy)carbonyl]-3,5-difluoro-<span class="text-smallcaps">L</span>-phenylalanine
• N-Boc-L-3,5-difluorophenylalanine
• N-(tert-Butoxycarbonyl)-3,5-difluoro-L-phenylalanine
• L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-3,5-difluoro-

N-Boc-3,5-difluoro-L-phenylalanine, 95%

CAS: 205445-52-9

Used as pharmaceutical intermediates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a par

Formula: C₁₄H₁₇F₂NO₄

Purity: 95%

Molecular weight: 301.29

Ref: 02-H62216

Boc-L-3,5-difluorophenylalanine

CAS: 205445-52-9

Formula: C₁₄H₁₇F₂NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 301.2859

Ref: IN-DA002A33

Boc-Phe(3,5-F2)-OH

CAS: 205445-52-9

Molecular weight: 301.29

Ref: 7W-GM4606

3,5-Difluoro-L-phenylalanine, N-BOC protected

CAS: 205445-52-9

3,5-Difluoro-L-phenylalanine, N-BOC protected

Formula: C₁₄H₁₇F₂NO₄

Purity: 98%

Color and Shape: white powder

Molecular weight: 301.29g/mol

Ref: 54-PC7119

BOC-3,5-difluoro-L-phenylalanine

CAS: 205445-52-9

Formula: C₁₄H₁₇F₂NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 301.29

Ref: 10-F095472