CAS 2055024-55-8

L-Ornithinamide, N-(13,13-dimethyl-1,11-dioxo-4,7,12-trioxa-10-azatetradec-1-yl)-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

Description:

L-Ornithinamide, N-(13,13-dimethyl-1,11-dioxo-4,7,12-trioxa-10-azatetradec-1-yl)-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- is a complex organic compound characterized by its unique structural features, including multiple functional groups and a long carbon chain. The presence of amide bonds suggests potential for biological activity, particularly in peptide synthesis or as a pharmaceutical intermediate. The compound contains both hydrophilic (hydroxymethyl and aminocarbonyl groups) and hydrophobic (dimethyl and aromatic components) characteristics, which may influence its solubility and interaction with biological membranes. The dioxo and trioxo moieties indicate potential reactivity, possibly allowing for further chemical modifications. Its specific stereochemistry, indicated by the L- prefixes, suggests chirality, which is crucial for biological activity. Overall, this compound's intricate structure may confer unique properties, making it of interest in medicinal chemistry and drug design, although detailed studies would be necessary to fully elucidate its behavior and applications.

Formula: C₃₀H₅₀N₆O₉

Synonyms:

• L-Ornithinamide, N-(13,13-dimethyl-1,11-dioxo-4,7,12-trioxa-10-azatetradec-1-yl)-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
• Boc-PEG2-Val-Cit-PAB-OH
• BocNH-PEG2-C2-Val-Cit-PAB-OH

tert-Butyl ((6S,9S)-1-amino-6-((4-(hydroxymethyl)phenyl)carbamoyl)-9-isopropyl-1,8,11-trioxo-14,17-dioxa-2,7,10-triazanonadecan-19-yl)carbamate

CAS: 2055024-55-8

tert-Butyl ((6S,9S)-1-amino-6-((4-(hydroxymethyl)phenyl)carbamoyl)-9-isopropyl-1,8,11-trioxo-14,17-dioxa-2,7,10-triazanonadecan-19-yl)carbamate

Purity: 95%

Molecular weight: 638.76g/mol

Ref: 54-OR1052929

Boc-PEG2-Val-Cit-PAB-OH

CAS: 2055024-55-8

Boc-PEG2-Val-Cit-PAB-OH is an enzymatically cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on PAB can be utilized for attachment to reactive groups (such as PNP) to connect with a drug payload. The Boc protecting group can be removed with acid, revealing a primary amine that serves for coupling reactions to form an amide. The Val-Cit-PAB segment is cleaved by cellular proteases, facilitating the effective release of the payload inside the cell.

Formula: C₃₀H₅₀N₆O₉

Color and Shape: Solid

Molecular weight: 638.753

Ref: TM-TYD-01991