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CAS 2055024-57-0

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L-Ornithinamide, N-[25-(9H-fluoren-9-yl)-1,23-dioxo-4,7,10,13,16,19,24-heptaoxa-22-azapentacos-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

Description:
L-Ornithinamide, N-[25-(9H-fluoren-9-yl)-1,23-dioxo-4,7,10,13,16,19,24-heptaoxa-22-azapentacos-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- is a complex organic compound characterized by its intricate structure, which includes multiple functional groups and a significant molecular weight. This substance features an ornithine derivative, indicating its potential relevance in biochemical applications, particularly in the context of amino acid metabolism or peptide synthesis. The presence of a fluorenyl group suggests potential applications in organic synthesis or as a fluorescent marker. Additionally, the compound contains hydroxymethyl and aminocarbonyl functionalities, which may enhance its reactivity and solubility in various solvents. Its unique structural components may also confer specific biological activities, making it a candidate for further research in medicinal chemistry or drug development. As with many complex organic molecules, its stability, solubility, and reactivity would depend on the specific conditions under which it is handled.
Formula:C48H68N6O13
Synonyms:
  • L-Ornithinamide, N-[25-(9H-fluoren-9-yl)-1,23-dioxo-4,7,10,13,16,19,24-heptaoxa-22-azapentacos-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
  • FmocNH-PEG6-C2-Val-Cit-PAB-OH
  • Fmoc-PEG6-Val-Cit-PAB-OH
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  • Fmoc-PEG6-Val-Cit-PAB-OH
    Targetmol
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    Fmoc-PEG6-Val-Cit-PAB-OH

    CAS:
    <p>Fmoc-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on PAB can be utilized to attach reactive groups (e.g., PNP) for drug payload conjugation. The Fmoc protecting group is removable with piperidine, revealing a primary amine for amide bond formation in conjugation reactions. The Val-Cit-PAB segment is cleaved by cellular proteases, enabling efficient payload release into cells.</p>
    Formula:C48H68N6O13
    Color and Shape:Solid
    Molecular weight:937.086

    Ref: TM-TYD-01888