CAS 205526-31-4

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-D-phenylalanine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-D-phenylalanine, commonly referred to as Fmoc-D-Tyr(3,4,5-F3)-OH, is a derivative of the amino acid phenylalanine, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group and trifluoromethyl substitutions. This compound is characterized by its unique structure, which includes a fluorenyl group that enhances its stability and solubility in organic solvents, making it useful in peptide synthesis. The trifluoromethyl groups contribute to its hydrophobicity and can influence the compound's reactivity and interaction with biological systems. Fmoc-D-Tyr(3,4,5-F3)-OH is typically utilized in solid-phase peptide synthesis, where the Fmoc group serves as a temporary protecting group for the amino group, allowing for the sequential addition of amino acids. Its properties, such as melting point, solubility, and reactivity, are influenced by the presence of the trifluoromethyl groups, which can also impart unique electronic characteristics. Overall, this compound is significant in the field of medicinal chemistry and peptide research due to its structural features and functional applications.

Formula: C₂₄H₁₈F₃NO₄

InChI: InChI:1S/C24H18F3NO4/c25-19-9-13(10-20(26)22(19)27)11-21(23(29)30)28-24(31)32-12-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-10,18,21H,11-12H2,(H,28,31)(H,29,30)

InChI key: InChIKey=VNMUACAZWGQRRL-OAQYLSRUSA-N

SMILES: C(OC(N[C@H](CC1=CC(F)=C(F)C(F)=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• <span class="text-smallcaps">D</span>-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-
• Fmoc-D-Phe(3,4,5-TriF)-OH
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-<span class="text-smallcaps">D</span>-phenylalanine
• Fmoc-D-3,4,5-Trifluorophenylalanine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-D-phenylalanine
• D-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3,4,5-TRIFLUOROPHENYLALANINE
• FMOC-D-PHE(3,4,5-F 3)-OH
• FMOC-D-PHE(M,P-F3)-OH
• FMOC-D-PHE(F)3-OH
• D-3,4,5-TRIFLUOROPHENYLALANINE, FMOC PROTECTED
• Fmoc-3,4,5-trifluoro-D-phenylalanine≥ 98% (HPLC)
• 3,4,5-Trifluoro-D-phenylalanine,N-FMOCprotected
• FMOC-3,4,5-TRIFLUORO-D-PHENYLALANINE
• (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Phe(3,4,5-TriF)-OH
• (2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(3,4,5-trifluorophenyl)propanoic acid
• Fmoc-D-2-Amino-3-(3,4,5-trifluoro-phenyl)alanine
• FMOC-D-3,4,5-TRIFLUOROPHENYLALANINE USP/EP/BP
• 3,4,5-TRIFLUORO-D-PHENYLALANINE FMOC PROTECTED
• FMOC-D-PHE(3,4,5-TRIFLUORO)-OH

D-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3,4,5-trifluoro-

CAS: 205526-31-4

Formula: C₂₄H₁₈F₃NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 441.3992

Ref: IN-DA002A64

3,4,5-Trifluoro-D-phenylalanine, N-FMOC protected

CAS: 205526-31-4

3,4,5-Trifluoro-D-phenylalanine, N-FMOC protected

Purity: 95%

Molecular weight: 441.40g/mol

Ref: 54-PC0504

(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4,5-trifluorophenyl)propanoic acid

CAS: 205526-31-4

Purity: 95%

Molecular weight: 441.4060059

Ref: 10-F737957