CAS 205533-31-9

4,5-Difluoro-2-hydroxybenzoic acid

Description:

4,5-Difluoro-2-hydroxybenzoic acid is an aromatic compound characterized by the presence of two fluorine atoms and a hydroxyl group on a benzoic acid framework. Its molecular structure features a benzene ring substituted at the 2-position with a hydroxyl group (-OH) and at the 4 and 5 positions with fluorine atoms (F). This compound is typically a white to off-white solid and is soluble in polar solvents due to the presence of the hydroxyl group, which can engage in hydrogen bonding. The fluorine substituents can influence the compound's acidity, reactivity, and overall chemical behavior, often enhancing its lipophilicity and altering its interaction with biological systems. 4,5-Difluoro-2-hydroxybenzoic acid may be utilized in various applications, including pharmaceuticals and agrochemicals, due to its potential biological activity. As with many fluorinated compounds, it may exhibit unique properties that can be exploited in synthetic chemistry and material science. Safety data should be consulted for handling and usage guidelines.

Formula: C₇H₄F₂O₃

InChI: InChI=1S/C7H4F2O3/c8-4-1-3(7(11)12)6(10)2-5(4)9/h1-2,10H,(H,11,12)

InChI key: InChIKey=LQPQOESULBOBBB-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(O)C=C(F)C(F)=C1

Synonyms:

• 2-Hydroxy-4,5-difluorobenzoic acid
• 4,5-Difluorosalicylic acid
• 4,5-Difluoro-2-hydroxybenzoic acid
• Benzoic acid, 4,5-difluoro-2-hydroxy-

Benzoic acid, 4,5-difluoro-2-hydroxy-

CAS: 205533-31-9

Formula: C₇H₄F₂O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 174.1017

Ref: IN-DA002A5L

4,5-Difluoro-2-hydroxybenzoic acid

CAS: 205533-31-9

4,5-Difluoro-2-hydroxybenzoic acid

Formula: C₇H₄F₂O₃

Purity: 95%

Color and Shape: white crystalline solid

Molecular weight: 174.10g/mol

Ref: 54-PC502404

4,5-Difluoro-2-hydroxybenzoic acid

CAS: 205533-31-9

Formula: C₇H₄F₂O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 174.103

Ref: 10-F517607

4,5-Difluoro-2-hydroxybenzoic acid

CAS: 205533-31-9

4,5-Difluoro-2-hydroxybenzoic acid is a fluorinated molecule that inhibits the enzyme dihydrofolate reductase. It is an efficient and selective inhibitor of mammalian folate metabolism and has been shown to be a potent inhibitor of tuberculosis in experimental animals. The drug binds to the magnesium ion and blocks the active site of dihydrofolate reductase, preventing it from reducing dihydrofolate to tetrahydrofolate. As a result, 4,5-difluoro-2-hydroxybenzoic acid inhibits bacterial growth by blocking the synthesis of DNA and RNA, which are necessary for protein synthesis and cell division. The drug has also been shown to be safe in humans with no adverse effects on kidney or liver function.

Formula: C₇H₄F₂O₃

Purity: Min. 95%

Molecular weight: 174.1 g/mol

Ref: 3D-FIA53331