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CAS 2055746-08-0

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  • EGFR-IN-159
    Targetmol
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    EGFR-IN-159

    CAS:
    EGFR-IN-159 (compound 12) is a dihydropyrimidine and a potent EGFR inhibitor with an IC50 of 29.00 nM. It exhibits dose-dependent inhibition of EGFR and HER2. The compound shows cytotoxicity against MCF-7 breast cancer cells and Vero cells with IC50 values of 16.07 μg/mL and 35.98 μg/mL, respectively. EGFR-IN-159 does not cross the blood-brain barrier (BBB) and demonstrates significant anticancer activity.
    Formula:C21H23N3O5
    Color and Shape:Solid
    Molecular weight:397.424

    Ref: TM-T206989

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