CAS 205678-31-5

(S)-2-(8-(2-(6-(methylamino)pyridin-2-yl)ethoxy)-3-oxo-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)acetic acid

Description:

The chemical substance known as (S)-2-(8-(2-(6-(methylamino)pyridin-2-yl)ethoxy)-3-oxo-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)acetic acid, with the CAS number 205678-31-5, is a complex organic compound characterized by its multi-cyclic structure and various functional groups. It features a benzo[c]azepine core, which is a bicyclic structure known for its presence in various pharmacologically active compounds. The presence of a methylamino group and a pyridine ring suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the trifluoroethyl group may enhance lipophilicity and metabolic stability. The (S) configuration indicates that it is a chiral molecule, which can influence its biological activity and pharmacokinetics. This compound may exhibit properties relevant to drug development, particularly in the context of neuropharmacology or other therapeutic areas, although specific biological activities would require empirical investigation. Overall, its intricate structure and functional diversity position it as a candidate for further research in pharmaceutical applications.

Formula: C₂₂H₂₄F₃N₃O₄

Synonyms:

• SB273005
• (S)-2-(8-(2-(6-(methylamino)pyridin-2-yl)ethoxy)-3-oxo-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)acetic acid USP/EP/BP
• 1H-2-Benzazepine-4-acetic acid, 2,3,4,5-tetrahydro-8-[2-[6-(methylamino)-2-pyridinyl]ethoxy]-3-oxo-2-(2,2,2-trifluoroethyl)-, (4S)-
• (S)-2-(8-(2-(6-(methylamino)pyridin-2-yl)ethoxy)-3-oxo-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)acetic acid
• [8-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-3-oxo-2-(2,2,2-trifluoro-ethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl]-acetic acid

(4S)-2,3,4,5-Tetrahydro-8-[2-[6-(methylamino)-2-pyridinyl]ethoxy]-3-oxo-2-(2,2,2-trifluoroethyl)-1H-2-benzazepine-4-acetic acid

CAS: 205678-31-5

Formula: C₂₂H₂₄F₃N₃O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 451.4389

Ref: IN-DA00BJNO

SB273005

CAS: 205678-31-5

SB273005

Purity: ≥98%

Molecular weight: 451.44g/mol

Ref: 54-BUP01943

SB273005

CAS: 205678-31-5

SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.

Formula: C₂₂H₂₄F₃N₃O₄

Purity: 99.58%

Color and Shape: Solid

Molecular weight: 451.44

Ref: TM-T6657

SB273005

CAS: 205678-31-5

SB273005 is a monoclonal antibody that binds to all-trans retinoic acid (ATRA) and prevents it from binding to ATRA receptors. This binding inhibits the production of growth factor-β1, collagen, and ATP in tumor cells. SB273005 has been shown to be effective in treating patients with glioma, as it decreases the size of tumors and prolongs survival time. The efficacy of SB273005 has also been demonstrated in tissue culture experiments on mouse glioma cells. The monoclonal antibody is administered intravenously by infusion over a period of 30 minutes each week for 3 weeks.

Formula: C₂₂H₂₄F₃N₃O₄

Purity: Min. 95%

Molecular weight: 451.44 g/mol

Ref: 3D-FIA67831