CAS 205701-85-5

5-(Ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxopyrido[1,2-a]benzimidazole-4-carboxamide

Description:

5-(Ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxopyrido[1,2-a]benzimidazole-4-carboxamide, with CAS number 205701-85-5, is a synthetic organic compound characterized by its complex structure, which includes a pyrido-benzimidazole core. This compound features multiple functional groups, including an ethoxymethyl group and a carboxamide, contributing to its potential biological activity. The presence of fluorine atoms suggests enhanced lipophilicity and may influence its pharmacokinetic properties. Typically, compounds of this nature are investigated for their potential therapeutic applications, particularly in the fields of medicinal chemistry and drug development. The structural intricacies may also impart specific interactions with biological targets, making it a candidate for further research in areas such as cancer treatment or other diseases. Its solubility, stability, and reactivity would depend on the specific conditions and solvents used, which are critical for understanding its behavior in biological systems. Overall, this compound exemplifies the complexity and diversity found in modern pharmaceutical chemistry.

Formula: C₂₁H₁₉F₂N₃O₃

InChI: InChI=1S/C21H19F2N3O3/c1-2-29-12-26-17-11-13(22)7-8-16(17)25-10-9-18(27)19(21(25)26)20(28)24-15-6-4-3-5-14(15)23/h3-8,11H,2,9-10,12H2,1H3,(H,24,28)

InChI key: InChIKey=VQOQDABVGWLROX-UHFFFAOYSA-N

SMILES: C(OCC)N1C=2N(C=3C1=CC(F)=CC3)CCC(=O)C2C(NC4=C(F)C=CC=C4)=O

Synonyms:

• 5-(Ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxopyrido[1,2-a]benzimidazole-4-carboxamide
• 5-(Ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxopyrido[1,2a]benzimidazole-4-carboxamide
• Pyrido[1,2-a]benzimidazole-4-carboxamide, 5-(ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxo-
• Rwj-51204

PYRIDO[1,2-A]BENZIMIDAZOLE-4-CARBOXAMIDE, 5-(ETHOXYMETHYL)-7-FLUORO-N-(2-FLUOROPHENYL)-1,2,3,5-TETRAHYDRO-3-OXO-

CAS: 205701-85-5

Formula: C₂₁H₁₉F₂N₃O₃

Purity: 95%

Molecular weight: 399.3907

Ref: IN-DA002AB8

RWJ-51204

CAS: 205701-85-5

RWJ-51204

Purity: ≥98%

Molecular weight: 399.39g/mol

Ref: 54-BUP12756

RWJ-51204

CAS: 205701-85-5

RWJ-51204 is a synthetic benzodiazepine that binds to the GABA receptor and has been shown to have anxiolytic properties. It has been shown to reduce the frequency of epileptiform activity in humans with severe dehydration and may be effective as an anti-epileptic drug. The clinical data on RWJ-51204 shows that it can be used for the treatment of anxiety disorders, such as posttraumatic stress disorder, obsessive-compulsive disorder, panic disorder, and social anxiety disorder. The drug substance is not currently available for sale in the United States but is being studied for its potential use in clinical trials. Doses of up to 5mg/kg have been found to be safe and well tolerated in human subjects. The effective dose of RWJ-51204 is 1mg/kg.

Formula: C₂₁H₁₉F₂N₃O₃

Purity: Min. 95%

Molecular weight: 399.4 g/mol

Ref: 3D-FIA70185

RWJ-51204

CAS: 205701-85-5

RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.

Formula: C₂₁H₁₉F₂N₃O₃

Purity: 99.57% - 99.95%

Color and Shape: Solid

Molecular weight: 399.39

Ref: TM-T16811