CAS 20575-57-9
:Calycosin
Description:
Calycosin, with the CAS number 20575-57-9, is a naturally occurring isoflavonoid primarily found in various plants, particularly in the roots of Astragalus species. It is known for its potential pharmacological properties, including antioxidant, anti-inflammatory, and estrogenic activities. Calycosin exhibits a chemical structure characterized by a benzene ring fused to a pyran ring, which is typical of isoflavones. This compound is often studied for its potential therapeutic effects, particularly in the context of traditional medicine and herbal remedies. In addition to its biological activities, calycosin has garnered interest in the field of natural product chemistry for its role in plant defense mechanisms and its potential applications in nutraceuticals. Its solubility properties can vary, and it is generally soluble in organic solvents while having limited solubility in water. As research continues, calycosin's full range of biological effects and mechanisms of action are being explored, highlighting its significance in both pharmacology and natural product research.
Formula:C16H12O5
InChI:InChI=1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8,17-18H,1H3
InChI key:InChIKey=ZZAJQOPSWWVMBI-UHFFFAOYSA-N
SMILES:O=C1C(=COC=2C1=CC=C(O)C2)C3=CC(O)=C(OC)C=C3
Synonyms:- 3′,7-Dihydroxy-4′-methoxyisoflavone
- 3′-Hydroxyformononetin
- 4H-1-benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-
- 7,3′-Dihydroxy-4′-methoxyisoflavone
- 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
- 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)benzopyran-4-one
- Calycosin
- Cyclosin
- Cyclosin (isoflavone)
- Isoflavone, 3′,7-dihydroxy-4′-methoxy-
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Calycosin
CAS:Formula:C16H12O5Purity:>98.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:284.27Calycosin (7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C16H12O5Color and Shape:PowderMolecular weight:284.068477-Hydroxy-3-(3-Hydroxy-4-Methoxyphenyl)-4H-Chromen-4-One
CAS:7-Hydroxy-3-(3-Hydroxy-4-Methoxyphenyl)-4H-Chromen-4-OneFormula:C16H12O5Purity:98%Molecular weight:284.26Calycosin
CAS:Calycosin, a major isoflavonoid isolated from Radix Astragal, induces angiogenesis in human umbilical vein endothelial cell cultures (HUVEC) in vitro and zebrafish embryos in vivo via the up-regulation of vascular endothelial growth factor (VEGF), VEGFR1 and VEGFR2 mRNA expression;it acts similar to other selective estrogen receptor modulators (SERMs) to promote angiogenesis via activation of MAPK with the involvement of ERK1/2 and ER. , such as raloxifene and tamoxifen, by displaying selective potency and affinity to estrogen receptors ERa and ERb.Formula:C16H12O5Purity:95%~99%Color and Shape:Yellow powderMolecular weight:284.267Calycosin
CAS:Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).Formula:C16H12O5Purity:99.91% - >99.99%Color and Shape:SolidMolecular weight:284.26Calycosin
CAS:7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-oneFormula:C16H12O5Purity:98%Molecular weight:284.26Calycosin
CAS:Oxygen-heterocyclic compoundFormula:C16H12O5Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:284.27Calycosin
CAS:Controlled ProductApplications Calycosin is a known antioxidant that prevent redox imbalance in organisms. Also, it possesses anti-tumor, anti-inflammation and osteogenic properties; Useful as a therapeutic reagent for bone loss-associated diseases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lu, L., et al.: J. Biosci. Bioeng., 124, 1-7 (2017); Quan, G., et al.: Int. J. Mol. Sci., 16, 29496-29507 (2015)Formula:C16H12O5Color and Shape:NeatMolecular weight:284.26Calycosin
CAS:Calycosin is a naturally occurring isoflavone, which is a class of organic compounds. It is derived primarily from the root of Astragalus membranaceus, a plant widely used in traditional Chinese medicine. As a prominent phytoestrogen, Calycosin exhibits a mode of action that includes binding to estrogen receptors, thereby influencing various estrogen-mediated biological processes.Formula:C16H12O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:284.26 g/molRef: 3D-FC10038
Discontinued product
