CAS 206010-80-2: Hypercalcemia Of Malignancy Factor (1-37) (Human, Rat)

Description: Hypercalcemia of Malignancy Factor (1-37) is a peptide that plays a significant role in the pathophysiology of hypercalcemia associated with malignancies. This factor is derived from parathyroid hormone-related peptide (PTHrP), which is often produced by certain tumors, leading to increased calcium levels in the blood. The peptide consists of 37 amino acids and exhibits structural similarities to parathyroid hormone, influencing calcium metabolism and bone resorption. Its primary function is to mimic the action of parathyroid hormone, stimulating osteoclast activity and promoting the release of calcium from bones into the bloodstream. This can result in various clinical manifestations, including weakness, confusion, and renal complications. The presence of Hypercalcemia of Malignancy Factor is particularly noted in certain cancers, such as squamous cell carcinoma of the lung and breast cancer. Understanding this factor is crucial for developing therapeutic strategies to manage hypercalcemia in cancer patients, as it highlights the interplay between tumor biology and calcium homeostasis.

Formula: C₁₉₇H₃₁₇N₆₃O₅₃

Synonyms:

• pTH-Related Protein (1-37) (human,mouse,rat)

pTH-Related Protein (1-37) (human, mouse, rat)

CAS: 206010-80-2

pTHrP (1-37) is a parathyroid hormone-related protein sequence implicated in malignant hypercalcemia.

• Formula: C₁₉₇H₃₁₇N₆₃O₅₃
• Purity: >98%
• Color and Shape: White Powder
• Molecular weight: 4416.08

pTH-Related Protein (1-37) (human, mouse, rat) trifluoroacetate salt

CAS: 206010-80-2

Please enquire for more information about pTH-Related Protein (1-37) (human, mouse, rat) trifluoroacetate salt including …

• Formula: C₁₉₇H₃₁₇N₆₃O₅₃
• Purity: Min. 95%
• Molecular weight: 4,416.02 g/mol