CAS 206055-75-6

DMT-2'-O-4'-C-Locked-T-CE-Phosphoramidite

Description:

DMT-2'-O-4'-C-Locked-T-CE-Phosphoramidite is a specialized chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a dimethoxytrityl (DMT) protecting group, which is crucial for the selective protection of the 5' hydroxyl group during oligonucleotide synthesis. The "2'-O-4'-C-Locked" designation indicates a specific structural modification that enhances the stability and binding properties of the nucleoside, often improving the overall efficiency of the synthesis process. The "T" refers to the thymidine base, while "CE" denotes a cyanoethyl group, which is commonly used in phosphoramidite chemistry to facilitate the coupling reactions. The phosphoramidite functional group allows for the formation of phosphodiester bonds, essential for linking nucleotides together. Overall, this compound is significant in the development of synthetic DNA and RNA, with applications in research, diagnostics, and therapeutic development. Its unique structural features contribute to its utility in producing high-fidelity oligonucleotides.

5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite

CAS: 206055-75-6

Formula: C₄₁H₄₉N₄O₉P

Purity: 95%

Color and Shape: Solid

Molecular weight: 772.8229

Ref: IN-DA01EFZI

Dmt-Loct Phosphoramidite

CAS: 206055-75-6

Dmt-Loct Phosphoramidite

Purity: 99%

Molecular weight: 772.82g/mol

Ref: 54-OR1025505

DMTr-LNA-5MeU-3-CED-phosphoramidite

CAS: 206055-75-6

DMTr-LNA-5MeU-3-CED-phosphoramidite

Purity: ≥98%

Molecular weight: 772.82g/mol

Ref: 54-BUP11705

DMTr-LNA-5MeU-3-CED-phosphoramidite

CAS: 206055-75-6

DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.

Formula: C₄₁H₄₉N₄O₉P

Purity: 98.28%

Color and Shape: Solid

Molecular weight: 772.82

Ref: TM-T13659

5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite

CAS: 206055-75-6

5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.

Formula: C₄₁H₄₉N₄O₉P

Purity: Min. 95%

Molecular weight: 772.82 g/mol

Ref: 3D-ND163164

DMTr-LNA-5MeU-3-CED-phosphoramidite

CAS: 206055-75-6

Purity: 95%

Molecular weight: 772.836

Ref: 10-F986818