Description:(S)-N-Fmoc-2,6-Dimethyltyrosine is a derivative of the amino acid tyrosine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group at the nitrogen atom of the amino group. This compound is notable for its chirality, as indicated by the (S) configuration, which refers to the specific spatial arrangement of its atoms. The presence of two methyl groups at the 2 and 6 positions of the aromatic ring enhances its hydrophobic properties, making it useful in peptide synthesis and other applications in medicinal chemistry. The Fmoc group serves as a protective moiety that can be easily removed under basic conditions, allowing for selective deprotection during peptide synthesis. This compound is often utilized in the development of peptide-based therapeutics and research due to its ability to mimic natural amino acids while providing additional functional versatility. Its CAS number, 206060-54-0, uniquely identifies this specific chemical substance in chemical databases, facilitating its recognition and study in various scientific contexts.
Applications N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine can be used as reactant/reagent in cyclic tetrapeptide ("Cyclodal") and its mirror-image isomer …
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