CAS 2060610-53-7

JBJ-04-125-02

CAS: 2060610-53-7

JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.

Formula: C₂₉H₂₆FN₅O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 543.61

Ref: TM-T11714

(2R)-2-(5-Fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide

CAS: 2060610-53-7

(2R)-2-(5-Fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide is a peptide that belongs to the class of inhibitors. It has been shown to inhibit ion channels in cells. The compound has an IC50 of about 0.25 μM for the hERG channel and shows no activity against other ion channels tested such as NMDA, GABA A , and Na V 1.8. (2R)-2-(5 -fluoro-- 2 -hydroxyphenyl)-2-[1 -oxo-- 6 - (4-- piperazin-- 1-- ylphenyl)-- 1,3 -dihydro-- 2H

Formula: C₂₉H₂₆FN₅O₃S

Purity: Min. 95%

Molecular weight: 543.6 g/mol

Ref: 3D-KHD61053