CAS 206184-49-8

Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1)

Description:

Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1) is a chemical compound characterized by its phosphonic acid functional group, which is known for its strong acidity and ability to form stable complexes with metal ions. This compound features a purine derivative, indicating potential biological activity, particularly in relation to nucleic acid metabolism or as a pharmaceutical agent. The presence of the methoxy group enhances its solubility and reactivity, while the amino group may contribute to its interaction with biological targets. As a hydrate, it contains water molecules in its structure, which can influence its stability and solubility in various solvents. The compound's unique structure suggests potential applications in medicinal chemistry, particularly in the development of antiviral or anticancer agents, given the biological significance of purine derivatives. Overall, this compound exemplifies the intersection of organic chemistry and biochemistry, with implications for drug design and therapeutic applications.

Formula: C₉H₁₄N₅O₄P·H₂O

InChI: InChI=1S/C9H14N5O4P.H2O/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14;/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17);1H2/t6-;/m1./s1

InChI key: InChIKey=PINIEAOMWQJGBW-FYZOBXCZSA-N

SMILES: C([C@H](OCP(=O)(O)O)C)N1C=2C(N=C1)=C(N)N=CN2.O

Synonyms:

• (R)-9-(2-phosphonylmethoxy propyl)adenine
• (R)-9-(2-phosphonylmethoxypropyl)adenine
• (R)-[[2-(6-Amino-9H-Purin-9-Yl)-1-Methylethoxy]Methyl]-Phosphonic Acid Monohydrate
• 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
• Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1)
• Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monohydrate
• Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monohydrate, (R)-
• Tenofovir monohydrate[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid monohydrate
• {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonic acid hydrate

Tenofovir

CAS: 206184-49-8

Compounds containing a pyrimidine ring (whether or not

Formula: C₉H₁₄N₅O₄P·H₂O

Color and Shape: White Powder

Molecular weight: 287.07834

Ref: 45-1643601

Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1)

CAS: 206184-49-8

Formula: C₉H₁₆N₅O₅P

Purity: 98%

Color and Shape: Solid

Molecular weight: 305.2276

Ref: IN-DA002AK1

Tenofovir hydrate

CAS: 206184-49-8

Tenofovir hydrate

Purity: ≥98%

Molecular weight: 305.23g/mol

Ref: 54-BUP13160

Tenofovir hydrate

CAS: 206184-49-8

Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.

Formula: C₉H₁₆N₅O₅P

Purity: 99.63%

Color and Shape: Solid

Molecular weight: 305.23

Ref: TM-T1649L

Tenofovir Monohydrate

Controlled Product

CAS: 206184-49-8

Stability Hygroscopic
Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.
References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);

Formula: C₉H₁₄N₅O₄P·H₂O

Color and Shape: Neat

Molecular weight: 305.23

Ref: TR-T185533

Tenofovir

CAS: 206184-49-8

Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI) with action on viral reverse transcriptase to block replication and is used for treating HIV/AIDS and chronic hepatitis B.

Formula: C₉H₁₄N₅O₄P·H₂O

Purity: Min. 95%

Molecular weight: 305.23 g/mol

Ref: 3D-GIA18449