CAS 20619-12-9

Monodesmethylchlorpheniramine

Description:

Monodesmethylchlorpheniramine, with the CAS number 20619-12-9, is a chemical compound that is a derivative of chlorpheniramine, an antihistamine commonly used to alleviate allergy symptoms. This substance is characterized by its ability to block histamine H1 receptors, thereby reducing allergic responses such as sneezing, itching, and runny nose. Monodesmethylchlorpheniramine is typically less potent than its parent compound, chlorpheniramine, and is often studied for its pharmacological properties and potential therapeutic applications. It is a lipophilic compound, which allows it to cross the blood-brain barrier, potentially leading to central nervous system effects such as sedation. The compound is usually found in a crystalline form and is soluble in organic solvents. Safety and toxicity profiles are important considerations, as with any pharmacologically active substance, and its use should be guided by appropriate medical advice. Overall, Monodesmethylchlorpheniramine serves as an important subject of study in the field of medicinal chemistry and pharmacology.

Formula: C₁₅H₁₇ClN₂

InChI: InChI=1/C15H17ClN2/c1-17-11-9-14(15-4-2-3-10-18-15)12-5-7-13(16)8-6-12/h2-8,10,14,17H,9,11H2,1H3

InChI key: InChIKey=UICFCNIVUDNZSW-UHFFFAOYSA-N

SMILES: C(CCNC)(C1=CC=C(Cl)C=C1)C2=CC=CC=N2

Synonyms:

• 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N-methyl-
• 2-Pyridinepropanamine, γ-(4-chlorophenyl)-N-methyl-
• Monodemethylchlorpheniramine
• Monodesmethylchlorpheniramine
• Pyridine, 2-[p-chloro-α-[2-(methylamino)ethyl]benzyl]-
• [3-(4-Chlorophenyl)-3-(pyridin-2-yl)propyl](methyl)amine
• γ-(4-Chlorophenyl)-N-methyl-2-pyridinepropanamine
• (3RS)-3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine
• CHLORPHEMINE IMPURITY C
• Chlorphenamine EP Impurity C HCl
• N-desmethylchlorpheniramine
• Chlorphenamine impurity C (Y0000437)
• YL)PROPAN-1-AMINE HYDROCHLORIDE
• Chlorphenamine impurity 3 monomer
• 3-(4-chlorophenyl)-N-methyl-3-pyridin-2-ylpropan-1-amine

CHLORPHENAMINE IMPURITY C CRS

CAS: 20619-12-9

CHLORPHENAMINE IMPURITY C CRS

Ref: 41-Y0000437

Monodesmethylchlorpheniramine

CAS: 20619-12-9

Monodesmethylchlorpheniramine

Purity: 98%

Ref: 54-OR1037253

Monodesmethylchlorpheniramine

Controlled Product

CAS: 20619-12-9

Impurity Chlorpheniramine EP Impurity C
Stability Air Sensitive
Applications Monodesmethylchlorpheniramine is an impurity of Chlorpheniramine (C424300), antihistaminic.
References Roth, F.E., et al.: J. Pharmacol. Exp. Ther., 124, 347 (1958), Smith, R.B., et al.: Toxicol. Appl. Pharmacol., 28, 240 (1974), Eckhart, C.G., et al.: Anal. Profiles Drug Subs., 7, 43 (1978)

Formula: C₁₅H₁₇ClN₂

Color and Shape: Neat

Molecular weight: 260.76

Ref: TR-M539520

3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine

CAS: 20619-12-9

Purity: 98%

Molecular weight: 260.108

Ref: 10-F569437