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CAS 2062-77-3

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trifluperidol hydrochloride

Description:
Trifluperidol hydrochloride is an antipsychotic medication belonging to the butyrophenone class, primarily used in the treatment of schizophrenia and other psychotic disorders. It acts as a dopamine antagonist, particularly at the D2 receptor, which helps in alleviating symptoms of psychosis. The compound is characterized by its white to off-white crystalline powder form, which is soluble in water and exhibits a pH range that is typically neutral to slightly acidic. Its chemical structure includes a trifluoromethyl group, contributing to its pharmacological properties. Trifluperidol hydrochloride is administered orally or via injection, and its therapeutic effects are often accompanied by potential side effects, including extrapyramidal symptoms and sedation. Due to its potency, careful dosage and monitoring are essential to minimize adverse reactions. As with many antipsychotics, it is important to consider individual patient factors when prescribing this medication. Overall, trifluperidol hydrochloride remains a significant option in the management of severe psychiatric conditions.
Formula:C22H23F4NO2·ClH
InChI:InChI=1/C22H23F4NO2.ClH/c23-19-8-6-16(7-9-19)20(28)5-2-12-27-13-10-21(29,11-14-27)17-3-1-4-18(15-17)22(24,25)26;/h1,3-4,6-9,15,29H,2,5,10-14H2;1H
InChI key:InChIKey=VYGQXRZAHIZHQV-UHFFFAOYSA-N
SMILES:OC1(C2=CC(C(F)(F)F)=CC=C2)CCN(CCCC(=O)C3=CC=C(F)C=C3)CC1.Cl
Synonyms:
  • 1-(4-Fluorophenyl)-4-{4-Hydroxy-4-[3-(Trifluoromethyl)Phenyl]Piperidin-1-Yl}Butan-1-One
  • 1-Butanone, 1-(4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)-1-piperidinyl)-, hydrochloride (9CI)
  • 1-Butanone, 1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-, hydrochloride
  • 1-Butanone, 1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-, hydrochloride (1:1)
  • 1-[4-(4-Fluorophenyl)-4-Oxobutyl]-4-Hydroxy-4-[3-(Trifluoromethyl)Phenyl]Piperidinium Chloride
  • 4'-Fluoro-4-(4-hydroxy-4-trifluoromethylphenylpiperidino)butyrophenone hydrochloride
  • Butyrophenone, 4'-fluoro-4-(4-hydroxy-4-(alpha,alpha,alpha-trifluoro-m-tolyl)piperidino)-, hydrochloride
  • Butyrophenone, 4'-fluoro-4-(4-hydroxy-4-(alpha,alpha,alpha-trifluoro-m-tolyl)piperidino)-, hydrochloride (VAN) (8CI)
  • Butyrophenone, 4′-fluoro-4-[4-hydroxy-4-(α,α,α-trifluoro-m-tolyl)piperidino]-, hydrochloride
  • Flumoperone hydrochloride
  • See more synonyms
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