CAS 2062-78-4: Pimozide
Description:Pimozide is an antipsychotic medication primarily used to treat Tourette syndrome and chronic tic disorders. It belongs to the diphenylbutylpiperidine class of compounds and functions as a dopamine antagonist, specifically targeting D2 dopamine receptors in the brain. Pimozide exhibits a high affinity for these receptors, which contributes to its therapeutic effects in managing symptoms associated with tic disorders. The substance is typically administered orally and is known for its long half-life, allowing for once-daily dosing in many cases. In terms of physical properties, pimozide is a white to off-white crystalline powder that is poorly soluble in water but soluble in organic solvents. It is important to monitor patients for potential side effects, which can include sedation, extrapyramidal symptoms, and cardiovascular effects. Due to its pharmacological profile, pimozide is classified as a prescription medication and should be used under the supervision of a healthcare professional.
Formula:C28H29F2N3O
InChI:InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChI key:InChIKey=YVUQSNJEYSNKRX-UHFFFAOYSA-N
SMILES:O=C1NC=2C=CC=CC2N1C3CCN(CCCC(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3
- Synonyms:
- 1-(1-(4,4-Bis(4-fluorophenyl)butyl)-4-piperindinyl)-1,3-dihydro-2H-benzimidazol-2-one
- 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
- 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazole-2-one
- 1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
- 1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine
- 2-Benzimidazolinone, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-
- Apo-Pimozide
- Nsc 170984
- Orap
- Pimozid
- See more synonyms
- Pimozida
- Pimozide
- Primozide
- R 6238
- 2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-