CymitQuimica logo

CAS 206260-33-5

:

Irampanel

Description:
Irampanel is a chemical compound primarily recognized as an antiepileptic drug. It functions as a selective antagonist of the AMPA receptor, which is a subtype of glutamate receptor in the central nervous system. This mechanism of action helps to modulate excitatory neurotransmission, making it effective in the treatment of epilepsy, particularly in patients with refractory seizures. Irampanel is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. The compound exhibits good bioavailability and is metabolized primarily in the liver, with its pharmacokinetics influenced by various factors, including age and concomitant medications. Common side effects may include dizziness, fatigue, and irritability, which are important considerations in clinical use. As with any medication, monitoring for adverse effects and interactions is crucial. Overall, Irampanel represents a significant advancement in the pharmacological management of epilepsy, providing an alternative for patients who do not respond adequately to traditional therapies.
Formula:C18H19N3O2
InChI:InChI=1S/C18H19N3O2/c1-21(2)12-13-22-16-11-7-6-10-15(16)18-19-17(20-23-18)14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3
InChI key:InChIKey=QZULPCPLWGCGSL-UHFFFAOYSA-N
SMILES:O(CCN(C)C)C1=C(C=CC=C1)C2=NC(=NO2)C3=CC=CC=C3
Synonyms:
  • Irampanel
  • BIIR 561
  • Ethanamine, N,N-dimethyl-2-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)phenoxy]-
  • N,N-Dimethyl-2-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)phenoxy]ethanamine
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.