CAS 206269-27-4

Levovirin

Description:

Levovirin, identified by its CAS number 206269-27-4, is an antiviral compound that has been studied for its potential in treating viral infections, particularly those caused by the human immunodeficiency virus (HIV). It is characterized by its ability to inhibit viral replication, making it a candidate for therapeutic applications in antiviral regimens. The substance is a nucleoside analog, which means it mimics the structure of natural nucleosides, thereby interfering with the viral life cycle. Levovirin's mechanism of action involves incorporation into viral RNA, leading to premature termination of viral genome synthesis. In terms of physical properties, Levovirin is typically presented as a white to off-white solid, and its solubility profile suggests it may be soluble in certain organic solvents while having limited solubility in water. Safety and efficacy profiles are critical in evaluating its use, and ongoing research continues to explore its potential benefits and side effects in clinical settings.

Formula: C₈H₁₂N₄O₅

InChI: InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m0/s1

InChI key: InChIKey=IWUCXVSUMQZMFG-RGDLXGNYSA-N

SMILES: O[C@@H]1[C@H](O[C@@H](CO)[C@@H]1O)N2N=C(C(N)=O)N=C2

Synonyms:

• 1-β-<span class="text-smallcaps">L</span>-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
• 1H-1,2,4-Triazole-3-carboxamide, 1-β-<span class="text-smallcaps">L</span>-ribofuranosyl-
• Icn-17261
• Levovirin
• R-1270
• 1H-1,2,4-Triazole-3-carboxamide, 1-β-L-ribofuranosyl-
• 1-β-L-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide

Levovirin

CAS: 206269-27-4

Levovirin (L-Ribavirin) is a guanosine nucleoside analog that has immunomodulatory activity and is used in the study of hepatitis C virus infection.

Formula: C₈H₁₂N₄O₅

Purity: 99.81% - >99.99%

Color and Shape: Solid

Molecular weight: 244.20

Ref: TM-T25702

Levovirin

CAS: 206269-27-4

Levovirin

Purity: ≥98%

Molecular weight: 244.2g/mol

Ref: 54-BUP07795

Levovirin

Controlled Product

CAS: 206269-27-4

Applications Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin (R414475) with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.
References Ramasamy, K.S. et al.: J. Med. Chem., 43, 1019 (2000); Fang, C. et al.: J. Appl. Toxicol., 23, 453 (2003):

Formula: C₈H₁₂N₄O₅

Color and Shape: Neat

Molecular weight: 244.20

Ref: TR-L379000

Levovirin

Controlled Product

CAS: 206269-27-4

Levovirin is an antiviral agent that belongs to the class of ribonucleotide reductase inhibitors. It is a potent inhibitor of hepatitis C virus replication and has been shown to be active against HIV in vitro. Levovirin acts as a competitive inhibitor of the NS3 protease, which is responsible for processing viral proteins. This inhibition prevents the production of new virus particles and the spread of infection. Levovirin also has immunomodulatory effects, which may provide therapeutic benefits in autoimmune diseases such as rheumatoid arthritis or Crohn's disease.

Formula: C₈H₁₂N₄O₅

Purity: Min. 95%

Molecular weight: 244.2 g/mol

Ref: 3D-IL167156