CAS 206449-93-6

2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide

Description:

The chemical substance known as 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide, with the CAS number 206449-93-6, is characterized by its complex molecular structure, which includes a furan ring, a sulfinyl group, and a piperidine moiety. This compound exhibits properties typical of sulfinamides, including potential biological activity due to its structural features that may interact with various biological targets. The presence of the furan ring suggests possible reactivity and participation in various chemical reactions, while the piperidine and pyridine components may contribute to its pharmacological properties. The compound's specific stereochemistry, indicated by the (2Z) configuration, may influence its biological activity and interactions. Overall, this substance is of interest in medicinal chemistry and pharmacology, potentially serving as a lead compound for further development in therapeutic applications. However, detailed studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₂₂H₂₉N₃O₄S

InChI: InChI=1/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-

InChI key: InChIKey=KMZQAVXSMUKBPD-DJWKRKHSNA-N

SMILES: C(C=1C=C(OC/C=C\CNC(CS(CC2=CC=CO2)=O)=O)N=CC1)N3CCCCC3

Synonyms:

• Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]-
• 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide
• Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-, (Z)-
• Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-
• (±)-Lafutidine
• rac Lafutidine
• (Z)-Lafutidine
• (Z)-FRG-8813

Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]-

CAS: 206449-93-6

Formula: C₂₂H₂₉N₃O₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 431.5484

Ref: IN-DA002IHU

(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide

CAS: 206449-93-6

(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide

Purity: 97%

Molecular weight: 431.56g/mol

Ref: 54-OR1059107

rac Lafutidine

Controlled Product

CAS: 206449-93-6

Applications Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.
References Onodera, S., et al.: Jpn. J. Pharmacol., 68, 161 (1995), Umeda, M., et al.: J. Gastroenterol. Heoatol., 14, 859 (1999), Ajioka, H., et al.: Pharmacology, 61, 83 (2000),

Formula: C₂₂H₂₉N₃O₄S

Color and Shape: White To Light Yellow

Molecular weight: 431.55

Ref: TR-L168500

rac Lafutidine

CAS: 206449-93-6

Lafutidine is a proton pump inhibitor that belongs to the class of H1 receptor antagonists. It is a potent and long lasting H1 receptor antagonist with a long half-life, which may be due to its ability to form a stable covalent bond with the active site of the enzyme. Lafutidine has been shown to inhibit gastric acid secretion in two-way crossover trials, reducing disease activity in patients with infectious diseases. It was also shown to increase water permeability in dextran sulfate sodium-induced ileitis models, although toxicity studies were not performed. Molecular docking analysis showed that lafutidine binds to the human serum albumin (HSA) binding site on the enzyme's active site, suggesting that it may have toxicological properties.

Formula: C₂₂H₂₉N₃O₄S

Purity: Min. 95%

Molecular weight: 431.55 g/mol

Ref: 3D-FR27533