CAS 206660-42-6

(2R)-Pinocembrin

Description:

(2R)-Pinocembrin, with the CAS number 206660-42-6, is a flavonoid compound primarily found in various plants, particularly in the family of the Zingiberaceae. This compound is characterized by its chiral structure, which includes a flavan backbone with a hydroxyl group at the 5-position and a methoxy group at the 7-position. It exhibits a pale yellow to white crystalline appearance and is soluble in organic solvents like ethanol and methanol, but less soluble in water. (2R)-Pinocembrin is known for its potential biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties, making it of interest in pharmacological research. Its stereochemistry plays a crucial role in its biological activity, as the (2R) configuration is associated with specific interactions in biological systems. Additionally, it is often studied for its potential health benefits, including its role in traditional medicine and its applications in nutraceuticals.

Formula: C₁₅H₁₂O₄

Synonyms:

• (2R)-Pinocembrin
• 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2R)-
• (R)-PinoceMbrin

4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2R)-

CAS: 206660-42-6

Formula: C₁₅H₁₂O₄

Color and Shape: Solid

Molecular weight: 256.2534

Ref: IN-DA002IM2

(R)-Pinocembrin

Controlled Product

CAS: 206660-42-6

Applications (2R)-Pinocembrin is the (R)-enantiomer of Pinocembrin, a flavanoid with antioxidant activity found in damiana, honey, and propolis. (2R)-Pinocembrin is a potential inhibitor of PIM1 kinase, an oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer.
References Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Holder, S. et al.: Mol. Cancer Ther., 6, 163 (2007); Holder, S. et al.: Bioorg. Med. Chem., 15, 6463 (2007);

Formula: C₁₅H₁₂O₄

Color and Shape: White

Molecular weight: 256.25

Ref: TR-P468505

(R)-Pinocembrin

CAS: 206660-42-6

(R)-Pinocembrin is a flavanone, which is a type of flavonoid compound. It is naturally sourced from a variety of plants, notably in honey, propolis, and certain fruits and vegetables. Its mode of action is primarily through its antioxidative and anti-inflammatory activities. (R)-Pinocembrin functions by scavenging free radicals, inhibiting inflammatory cytokines, and modulating various cellular pathways, which can impact oxidative stress and inflammation at a molecular level.

Formula: C₁₅H₁₂O₄

Purity: Min. 95%

Molecular weight: 256.25 g/mol

Ref: 3D-GIA66042

(-)-Pinocembrin

CAS: 206660-42-6

(-)-Pinocembrin: Anti-tuberculosis (IC50: 1.11 mg/mL dormant, 1.21 mg/mL active), antiproliferative (IC50: 1.88-11 mg/mL on various cell lines).

Formula: C₁₅H₁₂O₄

Color and Shape: Solid

Molecular weight: 256.25

Ref: TM-T72742