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CAS 2068-89-5

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<span class="text-smallcaps">L</span>-myo-Inositol 1,4,5-trisphosphate

Description:
L-myo-Inositol 1,4,5-trisphosphate (IP3) is a crucial signaling molecule in cellular processes, particularly in the regulation of intracellular calcium levels. It is derived from phosphatidylinositol 4,5-bisphosphate (PIP2) through the action of phospholipase C. Structurally, it is characterized by a six-membered cyclohexane ring with three hydroxyl groups at the 1, 4, and 5 positions, which play a significant role in its biological activity. IP3 is highly soluble in water, allowing it to diffuse rapidly within the cytoplasm. Its primary function involves binding to specific receptors on the endoplasmic reticulum, leading to the release of calcium ions into the cytosol, which subsequently triggers various cellular responses, including muscle contraction, secretion, and cell growth. The compound is also involved in various signaling pathways, including those related to hormone action and neurotransmission. Due to its pivotal role in cell signaling, L-myo-Inositol 1,4,5-trisphosphate is of significant interest in pharmacology and biochemistry.
Formula:C6H15O15P3
InChI:InChI=1S/C6H15O15P3/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1-,2+,3+,4-,5-,6-/m0/s1
InChI key:InChIKey=MMWCIQZXVOZEGG-HOZKJCLWSA-N
SMILES:O(P(=O)(O)O)[C@@H]1[C@@H](OP(=O)(O)O)[C@H](O)[C@H](O)[C@H](OP(=O)(O)O)[C@H]1O
Synonyms:
  • L-myo-Inositol 1,4,5-trisphosphate
  • D-myo-Inositol, 3,5,6-tris(dihydrogen phosphate)
  • Ins(3,5,6)P3
  • Inositol, 1,4,5-tris(dihydrogen phosphate), L-myo-
  • L-myo-Inositol 1,4,5-triphosphate
  • L-myo-Inositol-1,4,5-triphosphate (sodium salt)
  • L-myo-Inositol-1,4,5-trisphosphate sodium salt
  • ZVCVTWVBDIPWPZ-FWMAINDVSA-K
  • L-myo-Inositol-1,4,5-trisphosphate sodium salt, 98%,
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