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CAS 207117-28-0

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FMOC-ALPHA-METHYL-L-SER

Description:
FMOC-alpha-methyl-L-serine, with the CAS number 207117-28-0, is a derivative of the amino acid serine, modified to include a fluorenylmethyloxycarbonyl (FMOC) protecting group. This compound is characterized by its ability to serve as a building block in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The FMOC group provides a protective mechanism for the amino group, allowing for selective reactions during the synthesis process. The alpha-methyl substitution enhances the steric bulk around the amino acid, which can influence the conformation and properties of the resulting peptides. FMOC-alpha-methyl-L-serine is typically used in research and pharmaceutical applications, particularly in the development of peptide-based drugs and biomolecules. Its solubility in organic solvents and stability under various reaction conditions make it a valuable reagent in synthetic chemistry. Additionally, the compound's structure contributes to its potential role in modulating biological activity, making it of interest in medicinal chemistry and biochemistry.
Formula:C19H19NO5
InChI:InChI=1S/C19H19NO5/c1-19(11-21,17(22)23)20-18(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16,21H,10-11H2,1H3,(H,20,24)(H,22,23)/t19-/m0/s1
InChI key:QJTSLFSLVWJFCO-IBGZPJMESA-N
SMILES:C[C@](CO)(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms:
  • FMOC-L-ALPHA-METHYLSERINE
  • FMOC-ALPHA-METHYL-L-SER
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-2-methylpropanoic acid
  • (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-hydroxy-2-Methylpropanoic acid
  • FMOC-(S)-2-AMINO-2-METHYL-3-HYDROXYPROPANOIC ACID
  • L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-
  • Fmoc-2-Me-Ser-OH
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-serine
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