CAS 207124-64-9

Calcein tetraethyl acid

Description:

Calcein tetraethyl acid, identified by its CAS number 207124-64-9, is a fluorescent dye commonly used in biological and chemical applications. This compound is characterized by its bright green fluorescence, which makes it valuable for various imaging techniques, particularly in microscopy and flow cytometry. It is often employed as a tracer in biological studies to visualize cellular processes, such as cell viability and membrane integrity. The dye exhibits high solubility in water and is typically used in aqueous solutions. Its fluorescence properties can be influenced by pH and the presence of metal ions, which can quench or enhance its emission. Additionally, calcein tetraethyl acid is non-toxic, making it suitable for use in live-cell imaging. The compound's stability under physiological conditions allows for prolonged observation of biological samples. Overall, calcein tetraethyl acid is a versatile tool in both research and clinical settings, providing insights into cellular functions and dynamics.

GLYCINE, N,N'-[(3',6'-DIHYDROXY-3-OXOSPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHENE]-4',5'-DIYL)BIS(METHYLENE)]BIS[N-(CARBOXYMETHYL)-

CAS: 207124-64-9

Formula: C₃₀H₂₆N₂O₁₃

Purity: 98%

Molecular weight: 622.5330

Ref: IN-DA002IV0

Fluorescein-4',5'-bis(methyliminodiacetic acid)

CAS: 207124-64-9

Fluorescein-4',5'-bis(methyliminodiacetic acid)

Purity: 98%

Color and Shape: Orange Powder

Molecular weight: 622.53g/mol

Ref: 54-BID2025

Fluorescein Bis(methylene)]bis[N-(carboxymethyl)glycine] Sodium Salt (Technical Grade)

Controlled Product

CAS: 207124-64-9

Applications Fluorescein Bis(methylene)]bis[N-(carboxymethyl)glycine] is an intermediate used in the synthesis of Calcein AM (C125400), which is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
References Feller, N., et al.: Br. J. Cancer, 72, 543 (1995); Dhar, S., et al.: Eur. J. Pharmacol., 346, 315 (1998); Essodaigui, M., et al.: Biochemistry, 37, 2243 (1998); Lemasters, J.J., et al.: Biochim. Biophys. Acta., 1366,177 (1998);

Formula: C₃₀H₂₆N₂O₁₃•xNa

Color and Shape: Neat

Molecular weight: 622.53 + x(22.99)

Ref: TR-F485290